PPAR gamma/NR1C3 Antibody

Peroxisome proliferators are non genotoxic carcinogens which are purported to exert their effect on cells through their interaction with members of the nuclear hormone receptor family termed peroxisome proliferator activated receptors (PPARs). Nuclear hormone receptors are ligand dependent intracellular proteins that stimulate transcription of specific genes by binding to specific DNA sequences following activation by the appropriate ligand. Studies indicate that PPARs are activated by peroxisome proliferators such as clofibric acid, nafenopin, and WY14,643, as well as by some fatty acids. It has also been shown that PPARs can induce transcription of acyl coenzyme A oxidase & cytochrome P450 (CYP450) A6 through interaction with specific response elements.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 2 applications: IF/IHC, WB.

Showing Publications 1 - 5 of 5.

Publications using NBP1-61399	Applications	Species
Park Y, An M, Kim J, Lim Y Antiobesity effect of ethanolic extract of Ramulus mori in differentiated 3T3-L1 adipocytes and high-fat diet-induced obese mice Journal of Ethnopharmacology 2020-01-01 [PMID: 31904494] (WB, Mouse)	WB	Mouse
Bae IH, Lee SH, Oh S et al. Mannosylerythritol lipids ameliorate ultraviolet A-induced aquaporin-3 downregulation by suppressing c-Jun N-terminal kinase phosphorylation in cultured human keratinocytes Korean J. Physiol. Pharmacol. 2019-03-01 [PMID: 30820155] (WB, Human)	WB	Human
Yiew NK, Chatterjee TK, Tang YL et al. Novel role for Wnt inhibitor APCDD1 in adipocyte differentiation: implications for diet-induced obesity. J. Biol. Chem. 2017-02-27 [PMID: 28242765] (WB, Human)	WB	Human
Jiang Y, Li L, Liu B et al. PPAR-gamma Upregulation Induced by Vagus Nerve Stimulation Exerts Anti-Inflammatory Effect in Cerebral Ischemia/Reperfusion Rats Med. Sci. Monit. 2015-01-27 [PMID: 25619160] (IF/IHC, Rat)	IF/IHC	Rat
Lutay N, Hakansson G, Alaridah N et al. Mycobacteria Bypass Mucosal NF-kB Signalling to Induce an Epithelial Anti-Inflammatory IL-22 and IL-10 Response. PLoS ONE 2014-02-03 [PMID: 24489729] (WB, Human)	WB	Human

Images	Ratings	Applications	Species	Date	Details
Enlarge	5 reviewed by: Karen Brami-Cherrier	IHC-FrFl	Mouse	01/21/2017	View Summary Application Immunohistochemistry Free-Floating Sample Tested Mouse brain Species Mouse Lot N/A Comments Comments Immunohistochemisty on paraformaldehyde-perfused mice. The antibody works perfectly from 1:100 until 1:2000.I used it in free floating section. Briefly, I did intracardiac perfusion with 4% paraformaldehyde (PFA). The brains were post fixed overnight in PFA4% and then cut on vibratome (30 microm). The slices were conserved in cryoprotectant at -20 C. The IHC was then performed on free floating section.
Enlarge	5 reviewed by: Verified Customer	WB	Human	10/07/2014	View Summary Application Western Blot Sample Tested Hela cells transfected with vector and PPARg overexpression plasmid Species Human

Array NBP1-61399

• PPAR gamma/NR1C3 Antibodies
• PPAR gamma/NR1C3 ELISA Kits
• PPAR gamma/NR1C3 Kit
• PPAR gamma/NR1C3 Lysates
• PPAR gamma/NR1C3 Proteins