PMP70 Antibody (NBP1-20871)

PMP70 Antibody

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PMP70 Antibody Summary:
Species:Hu, Mu, Rt
Applications:PEP-ELISA
Clonality:Polyclonal
Gene:ABCD3
Purity:Immunogen affinity purified
Host:Goat
Specificity:This antibody is expected to recognize one isoform (NP_002849.1) only.
Publications:Antibody has at least 1 Background Reference.
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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PMP70 Antibody Details:
Isotype:IgG
Immunogen:Synthetic peptide, C-PDGREDQKRKGISD, representing the C terminusof the sequence according to NP_002849.1
Marker:Proxisomal Membrane Marker
Epitope:C terminus
Species Reactivity:

Human, Mouse, Rat

Applications:
Uses:Peptide ELISA: antibody detection limit dilution 1:16,000. Western Blot: Approx. 70kDa band observed in Human Kidney lysates (calculated MW of 75.5kDa according to NP_002849.1). Recommended concentration: 0.2-0.6 ug/ml.
Dilutions:Peptide ELISA 1:32000
Unit Size:0.1 mg
Concentration:0.5 mg/ml
Packaging:
Storage:Aliquot and store at -20 °C or -80 °C. Avoid freeze-thaw cycles.
Buffer:Tris-saline [pH7.3] with 0.5% BSA
Preservative:0.02% Sodium Azide
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: ABCD3
Entrez5825 (Human)
19299 (Mouse)
25270 (Rat)
Swiss ProtNP_002849.1 (Human)
 
Background:

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein likely plays an important role in peroxisome biogenesis. Mutations have been associated with some forms of Zellweger syndrome, a heterogeneous group of peroxisome assembly disorders. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

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Working with PMP70

PMP70 Antibody Images (1)
Western blot: ABCD3 Antibody [NBP1-20871]-(0.2µg/ml) staining of Human Kidney lysate (35µg protein in RIPA buffer).
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Publications (1)

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Jump to: Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies

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PMP70 in Context


Research Areas related to PMP70 (6):
Novus Explorer for PMP70 gene

Try our bioinformatic tool that shows the relationships between ABCD3 and other genes, diseases, pathways and post-translational modifications.