PMP22 Antibody (Hu1) Summary
||Human, Primate, Bovine (Negative), Mouse (Negative), Rat (Negative)
||WB, IHC, IHC-P
Protein G purified
All of our products are backed by our 100% guarantee to work for stated and predicted species and applications.
Test in a species/application not listed above to receive a full credit towards a future purchase.
PMP22 Antibody (Hu1) Details
Schwann Cell Marker
Detects amino acids 121-123 in the second extracellular domain of human PMP22.
Human PMP22 cDNA boosted with a 13-amino acid peptide of the 2nd extracellular domain (a.a. 120-133) conjugated to murine IgG. [Swiss-Prot# Q01453]
Human and Rhesus monkey. Does not react with mouse, rat, or bovine nerve protein.
||Read Publications using NB110-59086 in the following species:
- Western Blot
- Immunohistochemistry 1:50-1:200
- Immunohistochemistry-Paraffin 1:50-1:200
This PMP22 antibody is useful for Immunohistochemistry-Paraffin. Western Blot was reported in scientific literature.
Read a Publication using
NB110-59086 in the following applications:
Frequently Purchased Together
Earn rewards points by submitting your review for PMP22 Antibody (NB110-59086). Be the first to review this product and earn double rewards points!
PMP22 Antibody (NB110-59086) has been mentioned in at least 1 publication
Earn rewards if you have published using PMP22 Antibody (NB110-59086).
Packaging, Storage & Formulations
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Tris-glycine, 150 mM NaCl
0.05% Sodium Azide
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed
for 1 year from date of receipt.
Alternate Names for PMP22 Antibody (Hu1)
- growth arrest-specific 3
Related Products by Gene
PMP22 (peripheral myelin protein-22) is an integral membrane glycoprotein of internodal myelin and comprises an estimated 2-5 % of total myelin protein contents of peripheral nervous system. Its functional importance is emphasized by the fact that PMP22 gene mutations are the most common causes for inherited peripheral nerve disorders, also known as CMT (Charcot-Marie-Tooth diseases). Mutations of PMP22 are responsible for more than half of all the patients with inherited peripheral neuropathies, including CMT1A/CMT- type-1A with trisomy of PMP22, hereditary neuropathy with liability to pressure palsies (HNPP) with heterozygous deletion of PMP22, and CMT1E with point mutations of PMP22. These PMP22 associated disorders disrupt the organization of myelin, and subsequently axonal integrity which is untimately responsible for disabilities in patients. While overexpression and point-mutations of the PMP22 gene produces gain-of-function phenotypes, PMP22 deletion results in a loss-of-function phenotype that reveals the normal physiological functions of the PMP22 protein.
Reviews for PMP22 Antibody (NB110-59086) (0)
There are no reviews for PMP22 Antibody (NB110-59086).
By submitting a review earn points towards our Rewards Program.
- 250 points for product review
- 500 additional points for an image with your product review
- Double points (500) if you are the first to review this product
- Double points (1000) if you are the first to review this product with an image
Have you used PMP22 Antibody (NB110-59086)? Submit your review and earn rewards points which can be used for merchandise & discounts.
Points can be redeemed for discounts and gift cards:
Publications for PMP22 Antibody (NB110-59086) (1)
Read what people are writing who have used PMP22 Antibody (NB110-59086).
We have publications tested in 1 confirmed species: Human.
We have publications tested in 2 applications: WB, IHC.
Have you published using PMP22 Antibody (NB110-59086)? Submit your review and earn rewards points which can be used for merchandise & discounts.
Filter By Application
Filter By Species
Product General Protocols
Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.
Ask a Scientist
Submit your question on below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us
FAQs for PMP22 (3)
- Does this antibody recognize ONLY human PMP22, or does it also recognize mouse PMP22? I am looking for something that will detect ONLY human cells, transplanted into a mouse brain.
- We have confirmed that this antibody does not detect the mouse protein so this would be a good candidate for you. I would recommend using a directly conjugated primary antibody, as this will eliminate some of the background you may see by using an anti mouse secondary in mouse brain.
- In the immunohistochemistry paraffin section protocol....the PBS buffer....should it be at certain pH?
- For IHC application, different labs cites the pH of PBS buffer in the range of 7.1 - 7.6 but most commonly used pH is pH 7.4 (this is what we use in our lab). You may use this PBS (pH 7.4) for making permeablization buffer, antibody diluent buffers and for making wash buffer. For more on the protocol that we use in our lab and for IHC-P troubleshooting suggestions, you may visit: IHC-P Protocol and IHC-P Troubleshooting.
- I was wondering what does Format 7C mean as far as anitbodies go?
- 7C is a fluorophore - it is useful for FLOW. The details of the fluor are (A=425, E=500)
Bioinformatics Tool for PMP22
Discover related pathways, diseases and genes to PMP22. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.
Diseases for PMP22
Discover more about diseases related to PMP22.
Pathways for PMP22
View related products by pathway.
Research Areas for PMP22
Find related products by research area.
PTMs for PMP22
Learn more about PTMs related to PMP22.
Blogs on PMP22
Check out the latest blog posts on PMP22.