Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Phosphatase and Tensin Homolog (PTEN) dephosphorylates lipids. Malfunctions in this contribute to many human cancers. PTEN induced putative kinase 1 (Pink1) was first discovered when researching the PTEN signaling pathway, thus Pink1 is also involved in many human cancers. It is found in the mitochondria and its homozygous C-terminus mutation has been implicated in the early development of Parkinson's disease.
Western Blot: Pink1 Antibody [NB100-493] - Western blot detection of murine PINK1 using NB100-493. 1: molecular weight marker. 2. MES cell Mitochondria (20 ug). 3. MES cytosol (20 ug). 4. MES nuclear (20 ug) as negative control. 5. Purified human cytochrome C (0.1 ug) as PINK1 negative control.