PINK1 Antibody

Species: Hu, Mu Applications: WB Clonality: Polyclonal	Gene: PINK1 Purity: Affinity purified Host: Rabbit
Specificity: Pink1 Publications: Antibody has been mentioned in at least 2 publications.
See All PINK1 Products See All PINK1 Related Products: Peptides and Proteins Primary Antibodies RNAi
*Note not all species have been tested for reactivity. Only those species listed have been tested. We cannot make any guarantees about additional reactivities or cross reactivities beyond those that have been tested. This antibody may or may not react with other species.

Immunogen:	An N-terminal region synthetic peptide made to the human Pink1 protein sequence (between residues 1-50).
Localization:	Mitochondrion.

Entrez:	65018 (Human)
	68943 (Mouse)
Swiss Prot:	Q9BXM7 (Human)
Related Genes:	PARK2, PARK7, SNCA, LRRK2, UCHL1, PTEN, ATP13A2, HTRA2, DNM1L, SOD1, CRMP1, MAPT, UTRN, DENR, DAPK2, CYCS, CASP3, TRIM50, UBB, UCHL3, TRAP1, RNF216, RPS27A, MUL1, UBC, UBA52, OPA1, MED12, PSEN1, MFN2, HSP84-3, NDRG1, AKT1, SLC6A3, HSP90AA1, HSP90AB1, HSP84-2, GBA, FOXO3, NFKB1

Phosphatase and Tensin Homolog (PTEN) dephosphorylates lipids. Malfunctions in this contribute to many human cancers. PTEN induced putative kinase 1 (Pink1) was first discovered when researching the PTEN signaling pathway, thus Pink1 is also involved in many human cancers. It is found in the mitochondria and its homozygous C-terminus mutation has been implicated in the early development of Parkinson's disease.

Reactivity:	Reacts with human and mouse.

Uses:	This antibody is useful for Western blot where a band is seen ~60 kDa.
Dilutions:	Western Blot - 1:500
Unit Size:	0.1ml (also available: 0.025ml (sample size))
Concentrations:	1.0 mg/ml
Conjugated Ab's:	5 conjugated antibodies

Buffer:	Tris-citrate/phosphate, [pH7-8].
Storage:	Store at 4C. Do not freeze.
Preservative:	0.1% Sodium Azide
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.