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PI 3-Kinase p110 gamma Antibody

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Product Details

Summary
Product Discontinued
View other related PI 3-Kinase p110 gamma Primary Antibodies

Order Details


    • Catalog Number
      NB100-66285
    • Availability
      Product Discontinued

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PI 3-Kinase p110 gamma Antibody Summary

Immunogen
Peptide with the sequence FERAKTWKSKIGN from the C terminus of the protein sequence according to the Entrez Gene accession number NP_003653
Specificity
NB100-66285 detects an epitope within the C-terminal (CT) region of human PIK3CG, a 120kD catalytic subunit of phosphoinositide 3-OH kinase-gamma (PI3K gamma); a molecule affecting signalling pathways regulating cell growth. PIK3CG is an important modulator of extracellular signals, and plays a major role in the maintenance of structure and function of epithelia. PIK3CG is also thought to play a role in the regulation of cytotoxicity in NK cells. Reduced PIK3CG expression is correlated to tumour invasiveness and metastasis in colorectal cancers, whilst polymorphisms in the PIK3CG gene have been linked to susceptibility to autism.
Clonality
Polyclonal
Host
Goat
Gene
PIK3CG
Purity
IgG purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot
Control
PI 3-Kinase p110 gamma Overexpression Lysate

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
TBS
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
IgG purified

Alternate Names for PI 3-Kinase p110 gamma Antibody

  • 1-phosphatidylinositol 3-kinase
  • EC 2.7.1
  • EC 2.7.1.153
  • p110-gamma
  • p120-PI3K
  • phosphatidylinositol 3 kinase gamma, p110 gamma
  • phosphatidylinositol 3-kinase catalytic 110-kD gamma
  • phosphatidylinositol 3-kinase, catalytic, gamma polypeptide
  • Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma
  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • phosphoinositide-3-kinase gamma catalytic subunit
  • phosphoinositide-3-kinase, catalytic, gamma polypeptide
  • PI 3Kinase p110 gamma
  • PI 3-Kinase p110 gamma
  • PI3CG
  • PI3K
  • PI3K-gamma
  • PI3Kgamma
  • PI3K-gamma
  • PI3-kinase subunit gamma
  • PIK3
  • PIK3CG
  • PtdIns-3-kinase subunit gamma
  • PtdIns-3-kinase subunit p110-gamma

Background

The pirin gene encodes a member of the cupin superfamily. The protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor, as well as B cell lymphoma 3-encoded oncoprotein, suggest that the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Control Lysate(s)

PI 3-Kinase p110 gamma Overexpression Lysate

Secondary Antibodies

 

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Bioinformatics

Gene Symbol PIK3CG
Entrez