PI 3 Kinase catalytic subunit gamma Antibody (NB100-66285)
PI 3 Kinase catalytic subunit gamma Antibody
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Distributor Data...
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anti-Iron binding nuclear protein antibody, anti-PIR antibody, |
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PI 3 Kinase catalytic subunit gamma Antibody Summary: | | Gene: | PIK3CG |
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| Purity: | IgG purified |
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| Host: | Goat |
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| | Specificity: | NB100-66285 detects an epitope within the C-terminal (CT) region of human PIK3CG, a 120kD catalytic subunit of phosphoinositide 3-OH kinase-gamma (PI3K gamma); a molecule affecting signalling pathways regulating cell growth. PIK3CG is an important modulator of extracellular signals, and plays a major role in the maintenance of structure and function of epithelia. PIK3CG is also thought to play a role in the regulation of cytotoxicity in NK cells. Reduced PIK3CG expression is correlated to tumour invasiveness and metastasis in colorectal cancers, whilst polymorphisms in the PIK3CG gene have been linked to susceptibility to autism. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional PI 3 Kinase catalytic subunit gamma Products PI 3 Kinase catalytic subunit gamma Antibody Details: | Isotype: | IgG |
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| Immunogen: | Peptide with the sequence FERAKTWKSKIGN from the C terminus of the protein sequence according to the Entrez Gene accession number NP_003653 |
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| Uses: | Western Blot |
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| Dilutions: | Western Blot |
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| Unit Size: | 0.1 mg |
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| Concentration: | 0.5 mg/ml |
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| Positive Controls: | 1 Positive Controls |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | Tris buffered saline |
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| Preservative: | 0.02% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: The pirin gene encodes a member of the cupin superfamily. The protein is an Fe(II)-containing nuclear protein expressed in all tissues of the body and concentrated within dot-like subnuclear structures. Interactions with nuclear factor I/CCAAT box transcription factor, as well as B cell lymphoma 3-encoded oncoprotein, suggest that the encoded protein may act as a transcriptional cofactor and be involved in the regulation of DNA transcription and replication.
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Related ProductsPositive ControlsAntibody Pairs (1)Lysates (1)Primary Antibodies (9)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| PI 3 Kinase catalytic subunit gamma Antibody (Y388) | NB110-57349 | Hu, Mu(-), Rt(-) | FACS, IP, WB | (1) | (4) | | | | PI 3 Kinase catalytic subunit gamma Antibody | NB100-1097 | Hu | IHC, PEP-ELISA | (1) | (1) | | | | PI 3 Kinase catalytic subunit gamma Antibody | PAB6232 | Ca, Hu, Mu | ELISA, WB | | | | | | PI 3 Kinase catalytic subunit gamma Antibody | PAB4070 | Hu | ELISA, IHC-P, WB | | | | | | PI 3 Kinase catalytic subunit gamma Antibody | PAB4069 | Hu | ELISA, IHC-P, WB | | | | | | ... and 4 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Goat IgG Antibody [FITC] | NB710-F | Gt | ICC, IHC-P | | | | | | Goat IgG Antibody [Biotin] | NB710-B | Gt | ELISA, ICC, IHC-P, WB | | | | | | Goat IgG Antibody [Alkaline Phosphatase] | NB710-AP | Gt | ELISA, ICC, IHC-P, WB | | | | | | Goat IgG Antibody [HRP] | NB710-H | Gt | ELISA, ICC, IHC-P, WB | | (4) | | | | Goat IgG Antibody [Cy3] | NB120-6949 | Gt | ELISA, FACS, ICC, IF, IHC-Fr, IHC-P | | | | | | See All » |
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