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PI 3-Kinase p110 gamma Antibody (Y388)

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Product Details

Summary
Product Discontinued
View other related PI 3-Kinase p110 gamma Primary Antibodies

Order Details


    • Catalog Number
      NB110-57349
    • Availability
      Product Discontinued

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PI 3-Kinase p110 gamma Antibody (Y388) Summary

Immunogen
A synthetic peptide of in the N-term of human PI3-K p110 gamma was used as an immunogen.
Isotype
IgG
Clonality
Monoclonal
Host
Rabbit
Gene
PIK3CG
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Flow Cytometry 1:50
  • Immunoprecipitation 1:50
  • Western Blot 1:1000
Application Notes
This product is useful for: Western Blot, Immunoprecipitation, Flow Cytometry. In Western blot this antibody detects a band at approximately 110kDa.
Control
PI 3-Kinase p110 gamma Overexpression Lysate

Reactivity Notes

Reacts with: Human Does not react with Mouse, Rat

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
49% PBS, 0.05% BSA and 50% Glycerol
Preservative
0.01% Sodium Azide
Purity
Protein A purified

Notes

Produced using Abcam's RabMab® technology. RabMab® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

Alternate Names for PI 3-Kinase p110 gamma Antibody (Y388)

  • 1-phosphatidylinositol 3-kinase
  • EC 2.7.1
  • EC 2.7.1.153
  • p110-gamma
  • p120-PI3K
  • phosphatidylinositol 3 kinase gamma, p110 gamma
  • phosphatidylinositol 3-kinase catalytic 110-kD gamma
  • phosphatidylinositol 3-kinase, catalytic, gamma polypeptide
  • Phosphatidylinositol-4,5-bisphosphate 3-kinase 110 kDa catalytic subunit gamma
  • phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • phosphoinositide-3-kinase gamma catalytic subunit
  • phosphoinositide-3-kinase, catalytic, gamma polypeptide
  • PI 3Kinase p110 gamma
  • PI 3-Kinase p110 gamma
  • PI3CG
  • PI3K
  • PI3K-gamma
  • PI3Kgamma
  • PI3K-gamma
  • PI3-kinase subunit gamma
  • PIK3
  • PIK3CG
  • PtdIns-3-kinase subunit gamma
  • PtdIns-3-kinase subunit p110-gamma

Background

PI3-Kinases (PI3-Ks) are a family of lipid kinases that are implicated in signal transduction. PI3-K consists of two subunits; p85 and p10. The p85 subunit localize PI3-K activity to the plasma membrane while the p110 subunit contains the catalytic domain of PI3-K (1-2). Four isoforms of p110 has been found; alpha, beta, gamma, and the delta subunit (3). The gamma isoform is most clostly related to p110 alpha, and beta and has been shown not to interact with p85 in vivo (4). It has been found that in p110-gamma protein expression is lost in primary colorectal adeno-carcinomas and in colon cancer cell lines (5)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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PI 3-Kinase p110
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NB110-57349
PI 3-Kinase p110 gamma Antibody (Y388)
Species: Hu, Mu(-), Rt(-)
Applications: WB, Flow, IP

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Control Lysate(s)

PI 3-Kinase p110 gamma Overexpression Lysate

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PIK3CG
Entrez
Uniprot