PDGFA Antibody (NBP1-72192) | Novus Biologicals

PDGFA Antibody (NBP1-72192) (100 ug)

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	Catalog Number	NBP1-72192
	Size(s)	100 ug	Price:
	Availability
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anti-platelet-derived growth factor subunit A antibody, anti-PDGF-1 antibody, anti-platelet-derived growth factor alpha isoform 2 preproprotein antibody, anti-Platelet-derived growth factor A chain antibody, anti-platelet-derived growth factor alpha chain antibody, anti-PDGF-A antibody, anti-PDGF1PDGF A-chain antibody, anti-platelet-derived growth factor alpha polypeptidePDGF subunit A antibody

PDGFA Antibody Summary:

Species:	Hu, Mu, Rt	Gene:	PDGFA
Applications:	WB, ELISA, IHC-P, IP	Purity:	Immunogen affinity purified
Clonality:	Polyclonal	Host:	Rabbit
Specificity:	This antibody recognizes ~23 kDa of human PDGF protein
Publications:	NBP1-72192 has been mentioned in at least 2 Publications

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PDGFA Antibody Details:

Immunogen:	A fusion recombinant protein derived from E Coli, containing 196aa- full length of human PDGF protein

Species Reactivity:

Reactive in Human, Rat, and Mouse

Applications:

Uses:	Useful in Western Blot, ELISA, Immunoprecipitation, and IHC
Dilutions:	ELISA 0.01-0.1 ug/ml, Immunohistochemistry-Paraffin 2-5 ug/ml, Immunoprecipitation 2-5 ug/ml, Western Blot 0.1-1 ug/ml
MW:	24 kDa
Unit Size:	100 ug
Concentration:	0.5 mg/ml
Positive Controls:	1 Positive Controls

Packaging:

Storage:	Store at 4°C short term. Aliquot and store at -20°C or -80°C. Avoid freeze-thaw cycles.
Buffer:	PBS (pH7.2) containing antibody stabilizer
Preservative:	No Preservative
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

Gene Symbol: PDGFA

Entrez:	5154 (Human)
	18590 (Mouse)
	25266 (Rat)
Uniprot:	P04085 (Human)

Related Genes:

Background:

The platelet-derived growth factor (PDGF) family of disulfide-linked dimeric proteins consists of homo/hetero dimeric proteins, PDGF-AA, -BB, -CC, -DD and -AB. The PDGF-AA, -BB and AB bind to alpha type receptor, while beta type receptors bind to PDGF-BB and PDGF-AB. Upon activation by PDGF, the receptors get dimerised and auphosphorylated in several sites on its receptors (Receptor tyrosine kinase) in cytosolic domain to trigger cell signaling through PI3K pathway. All PDGF isoforms are synthesized as inactive precursors and are processed to active forms.

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