Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
This antibody was produced from a hybridoma (mouse myeloma fused with
spleen cells from a mouse immunized with human PDGF-AA recombinant protein.
Species Reactivity:
This antibody is reactive against human. Not yet tested in other species.
Applications:
Uses:
In western blots this antibody shown no cross-reactivity with E-Cadherin, and P-Cadherin. In Western blot
Dilutions:
Western Blot 1:1000-1:2000,
Unit Size:
0.1 mg
Concentration:
lyoph
Packaging:
Storage:
Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles.
Buffer:
Lyophilized - Reconstitute the antibody with 500 ul sterile PBS and the final concentration is 200ug/ml.
Preservative:
No Preservative
Limitations:
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
PDGF AA is a member of the platelet derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. PDGF AA can exist either as a homodimer or as a heterodimer with the platelet derived growth factor beta polypeptide, where the dimers are connected by disulfide bonds. Studies using knockout mice have shown cellular defects in oligodendrocytes, alveolar smooth muscle cells, and Leydig cells in the testis; knockout mice die either as embryos or shortly after birth.
Formalin fixed and Paraffin embedded human placenta tissue section was subjected to IHC staining using NB110-60979 (Proteinase K pretreatment is required).