PARP Antibody (NB100-61616)
PARP Antibody
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Distributor Data...
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anti-PARP antibody, anti-PPOL antibody, anti-poly(ADP-ribose) polymerase. antibody, anti-Poly (ADP-ribose) Polymerase Family antibody, anti-PARP-1 antibody, anti-PARP1 antibody, anti-member 1 antibody, anti-ADPRT1 antibody, anti-ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase) antibody, anti- ADPRT antibody, |
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PARP Antibody Summary: | | Gene: | PARP1 |
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| Purity: | Immunogen affinity purified |
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| Host: | Rabbit |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional PARP Products PARP Antibody Details: | Isotype: | IgG |
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| Immunogen: | The epitope recognized by this antibody maps to a region between residue 50 and 100 of human poly (ADP-ribose) polymerase family, member 1 using the numbering given in entry NP_001609.1 (GeneID 142). |
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| Uses: | This antibody is useful for Western Blot |
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| Dilutions: | Immunohistochemistry-Paraffin 1:100 - 1:500, Western Blot 1:2000-1:10000 |
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| Unit Size: | 0.1 ml |
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| Concentration: | 0.2 mg/ml |
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Notes: IHC Caption A - Detection of Human PARP1 by Immunohistochemistry. Sample: FFPE section of human breast carcinoma. Antibody: Affinity purified rabbit anti-PARP1 used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit. IHC Caption B - Detection of Human PARP1 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-PARP1 used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit. Packaging: | Storage: | Store at 4 °C. Do not freeze. |
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| Buffer: | Tris-buffered Saline containing 0.1% BSA |
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| Preservative: | 0.09% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: PARP1 (Poly-ADP-ribose polymerase 1) is a member of PARP family of enzymes that transfer the ADP-D-ribosyl group of NAD(+) to an acceptor carboxyl group on proteins. PARP1 catalyzes the poly-ADP-ribosylation of histone and non-histone proteins in response to DNA damage. The over-activation of PARP-1 in response to DNA damage has been shown to promote cell and tissue injury. This observation has initiated research into the therapeutic potential of PARP1 inhibitors in the treatment of cancer, cardiovascular disease, and brain injury.
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Images (3) Reviews (0) Related Products (27) Exploring PARP
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Jump to: Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPeptides and ProteinsPrimary Antibodies (17)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| PARP Antibody (C-2-10) | NB100-111 | Bv, Ch(-), Ha, Hu, Mk, Mu, Rt | ELISA, ICC, WB | (1) | (3) | | | | PARP Antibody (E102) | NB110-57323 | Hu, Mu(-), Rt | FACS, ICC, IHC-P, WB | (4) | (1) | | | | PARP Antibody (A6.4.12) | NB100-64828 | Dr, Hu, Mu, Rt, Xp | ELISA, IF, IHC-Fr, IHC-P, IP, WB | (1) | (3) | | | | PARP Antibody | NSB698 | Bv, Hu | ICC, WB | (2) | (2) | | | | PARP Antibody (3G4) | H00000142-M01 | Hu | ELISA, IF, WB | (3) | (1) | | | | ... and 12 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Rabbit IgG Antibody [HRP] | NB730-H | Rb | ELISA, ICC, IHC-P, WB | | (5) | | | | Rabbit IgG Antibody [FITC] | NB730-F | Rb | ICC, IHC-P | | (1) | | | | Rabbit IgG Antibody [Biotin] | NB730-B | Rb | ELISA, ICC, IHC-P, WB | | | | | | Rabbit IgG, H/L Chains Antibody [DyLight 488] | NBP1-72944 | Rb | FLISA, IF, WB | (3) | | | | | Rabbit IgG Antibody [Alkaline Phosphatase] | NB730-AP | Rb | ELISA, ICC, IHC-P, WB | | (1) | | | | See All » |
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![Western Blot: PARP1 Antibody [NB100-61616] - Detection of Human PARP1 by Western Blot. Samples: Whole cell lysate (5, 15 and 50 ug) from 293T cells. Antibody: Affinity purified rabbit anti-PARP1 antibody NB100-61616 used for WB at 0.04 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.](http://images.novusbio.com/images/p_61616_1.jpg "Western Blot: PARP1 Antibody [NB100-61616] - Detection of Human PARP1 by Western Blot. Samples: Whole cell lysate (5, 15 and 50 ug) from 293T cells. Antibody: Affinity purified rabbit anti-PARP1 antibody NB100-61616 used for WB at 0.04 ug/ml. Detection: Chemiluminescence with an exposure time of 30 seconds.")
![Immunohistochemistry-Paraffin: PARP Antibody [NB100-61616] - See Notes, IHC Caption A](http://images.novusbio.com/images/PARP Antibody-Immunohistochemistry-Paraffin-NB100-61616-img0001.jpg "Immunohistochemistry-Paraffin: PARP Antibody [NB100-61616] - See Notes, IHC Caption A")
![Immunohistochemistry-Paraffin: PARP Antibody [NB100-61616] - See Notes, IHC Caption B](http://images.novusbio.com/images/PARP Antibody-Immunohistochemistry-Paraffin-NB100-61616-img0002.jpg "Immunohistochemistry-Paraffin: PARP Antibody [NB100-61616] - See Notes, IHC Caption B")
