Nuclear Receptor SHP Lysate (NBL1-13765)
Nuclear Receptor SHP Lysate
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Distributor Data...
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FLJ17090, SHP1, SHP, |
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Nuclear Receptor SHP Lysate Summary: | | | Specificity: | Homo sapiens nuclear receptor subfamily 0, group B, member 2 (NR0B2), mRNA. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional Nuclear Receptor SHP Products Nuclear Receptor SHP Lysate Details: | Immunogen: | The lysate was created in HEK293T cells, using plasmid ID RC206422 and based on accession number NM_021969. The protein contains a C-terminal DDK tag. |
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Lysate Details: | Type: | Overexpression | Life Stage: | Adult | | Protein State: | Native | Tissue Condition: | Normal | | Sub-cellular Fraction: | Whole |
| Uses: | This product is intended for use as a positive control in Western Blot. You will receive the lysate (100ug), and an empty vector negative control (100 ug). |
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| Dilutions: | Western Blot |
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| TMW: | 27.9 kDa |
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| Unit Size: | 0.1 mg |
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| Concentration: | 1.0 mg/ml |
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Notes: This product is manufactured by and sold under license from OriGene Technologies and its use is limited solely for research purposes. Please note that “1 mg/ml” refers to the total protein concentration and that the specific protein concentration is not determined at this time. Packaging: | Storage: | Store at -80 °C. Avoid freeze-thaw cycles. |
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| Buffer: | RIPA buffer |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: The protein encoded by this gene is an unusual orphan receptor that contains a putative ligand-binding domain but lacks a conventional DNA-binding domain. The gene product is a member of the nuclear hormone receptor family, a group of transcription factors regulated by small hydrophobic hormones, a subset of which do not have known ligands and are referred to as orphan nuclear receptors. The protein has been shown to interact with retinoid and thyroid hormone receptors, inhibiting their ligand-dependent transcriptional activation. In addition, interaction with estrogen receptors has been demonstrated, leading to inhibition of function. Studies suggest that the protein represses nuclear hormone receptor-mediated transactivation via two separate steps: competition with coactivators and the direct effects of its transcriptional repressor function. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
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Nuclear Receptor SHP Lysate Images (1) Western Blot: Nuclear Receptor SHP Lysate [NBL1-13765] - Western Blot experiments.
Left-Control; Right -Over-expression Lysate for NR0B2 |
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