NFkB p65 Antibody (NBP1-02913)
NFkB p65 Antibody
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Distributor Data...
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anti-RELA antibody, NFKB3 antibody, MGC131774 antibody, |
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NFkB p65 Antibody Summary: | | Gene: | RELA |
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| Purity: | Delipidation and Defibrination |
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| Host: | Rabbit |
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| | Specificity: | NFkB p65 (Rel A) peptide corresponding to a region near the C-terminus of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH). |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional NFkB p65 Products NFkB p65 Antibody Details: | Immunogen: | NFkB p65 (Rel A) peptide corresponding to a region near the C-terminus of the human protein conjugated to Keyhole Limpet Hemocyanin (KLH) |
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This antibody is reactive to Human. |
| Uses: | This antibody is useful for the following applications and at the following dilutions: Western Blot, immunoprecipitation, ELISA, immunofluorescence, Immunohistochemistry-Paraffin 1:500, Gel Super Shift Assays |
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| Dilutions: | Western Blot, immunoprecipitation, ELISA, immunofluorescence, Immunohistochemistry-Paraffin 1:500, Gel Super Shift Assays, |
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| Unit Size: | 0.05 ml |
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| Concentration: | 90.0 mg/ml |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Preservative: | 0.01% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: NFkB was originally identified as a factor that binds to the immunoglobulin kappa light chain enhancer in B cells. It was subsequently found in non-B cells in an inactive cytoplasmic form consisting of NFkB bound to IkB. NFkB was originally identified as a heterodimeric DNA binding protein complex consisting of p65 (RelA) and p50 (NFKB1) subunits. Other identified subunits include p52 (NFKB2), c-Rel, and RelB. The p65, cRel, and RelB subunits are responsible for transactivation. The p50 and p52 subunits possess DNA binding activity but limited ability to transactivate. p52 has been reported to form transcriptionally active heterodimers with the NFkB subunit p65, similar to p50/p65 heterodimers. The heterodimers of p52/p65 and p50/p65 are regulated by physical inactivation in the cytoplasm by IkB-a. IkB-a binds to the p65 subunit, preventing nuclear localization and DNA binding. Low levels of p52 and p50 homodimers can also exist in cells.
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Images (2) Reviews (0) Related Products (91) Exploring NFkB p65
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Working with NFkB p65
NFkB p65 Antibody Images (2) Staining of Formalin-Fixed Paraffin-Embedded (FFPE) human spleen using NBP1-02913 |  Staining of Formalin-Fixed Paraffin-Embedded (FFPE) human kidney using NBP1-02913 |
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Jump to: Antibody Pairs, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsAntibody Pairs (8)Lysates (1)Peptides and ProteinsPrimary Antibodies (40)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| NFkB p65 Antibody | NBP1-96139 | Hu, Mk, Mu | ICC, IF, IHC-P, WB | (3) | | | | | NFkB p65 Antibody | NBP1-96138 | Hu, Mk, Mu | ICC, IF, IHC-P | (2) | | | | | NFkB p65 Antibody (E379) | NB110-57267 | Hu, Mu | FACS, ICC, IHC-P, IP, WB | (3) | (1) | | | | NFkB p65 Antibody (27F9.G4) | NBP1-77815 | Hu | ELISA, IF, IHC-P, WB | (4) | | | | | NFkB p65 Antibody | NB100-2176 | Hu, Mu, Rt | IHC-P, IP, WB | (3) | (1) | | | | ... and 35 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Rabbit IgG Antibody [HRP] | NB730-H | Rb | ELISA, ICC, IHC-P, WB | | (5) | | | | Rabbit IgG Antibody [FITC] | NB730-F | Rb | ICC, IHC-P | | (1) | | | | Rabbit IgG Antibody [Biotin] | NB730-B | Rb | ELISA, ICC, IHC-P, WB | | | | | | Rabbit IgG, H/L Chains Antibody [DyLight 488] | NBP1-72944 | Rb | FLISA, IF, WB | (3) | | | | | Rabbit IgG Antibody [Alkaline Phosphatase] | NB730-AP | Rb | ELISA, ICC, IHC-P, WB | | (1) | | | | See All » |
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