mGluR2 Antibody Summary
| Immunogen |
This polyclonal antibody was raised by immunizing rabbit with a synthetic peptide containing amino acids on the predicted extracellular domain (20-400) of human GRM2. |
| Specificity |
glutamate receptor, metabotropic 2 (Grm2) |
| Clonality |
Polyclonal |
| Host |
Rabbit |
| Gene |
GRM2 |
| Purity |
Immunogen affinity purified |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
| Dilutions |
|
| Application Notes |
The antiserum titer is about 97K for ELISA. It has not been tested in the other applications. However, for the first testing, we recommend1/3,000 dilution for ELISA, 1/500 dilution for Western blot analysis (WB) of recombinant protein, 1/400 dilution for tissue extracts or cell lysates, 1/20 dilution for immunohistochemistry staining on frozen cryosections, 1/1dilution for IHC staining on paraffin embedded sections. |
Reactivity Notes
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Buffer |
No buffer |
| Preservative |
No Preservative |
| Concentration |
LYOPH |
| Purity |
Immunogen affinity purified |
| Reconstitution Instructions |
Please contact technical support for detailed reconstituion instruction. |
Alternate Names for mGluR2 Antibody
Background
Glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. The metabotropic glutamate receptors are a family of G protein-coupled receptors that have been divided into 3 groups. GRM2 is a receptor for glutamate and is a member of the Group II of G protein coupled receptor family (subfamily metabotropic glutamate). GRM2 receptor is linked to the inhibition of the cyclic AMP cascade and has been reported primarily in the brain. ESTs have been isolated from B-cell/lung/testis, brain, breast, kidney, and testis libraries.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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FAQs for mGluR2 Antibody (NBP1-04733) (0)
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