14-3-3 Lysate

Applications: WB

Gene: YWHAQ Purity: Protein

Specificity:	Homo sapiens tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta polypeptide (YWHAQ), mRNA.

Immunogen:	The lysate was created in HEK293T cells, using plasmid ID RC208646 and based on accession number NM_006826.

Type: Overexpression Tissue Condition: Normal

Life Stage: Adult Protein State: Native Sub-cellular Fraction: Whole

Entrez:	10971 (Human)
Swiss Prot:	NM_006826 (Human)
Related Genes:	MAPT, MAPT, MAPT, TH, CSNK1E, AKT1, PRNP, AKT1, LAMC2, AKT1, RAF1, MAPK1, MAPK1, CDC25C, CDC25C, PIK3CG, BCL2L1, BCL2L1, BCL2L1, RAF1, CASP3, MAPK8, MAPK1, PRNP, TNF, RAF1, PTK2B, CHEK1, CHEK1, GSTP1, CHEK1, GSTA4, ZHX2, PRKACA, RASGRF1, MAPK8, ZHX2, ZHX2, HCLS1, GSK3B

This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence which is polymorphic, however, there is no correlation between the repeat number and the disease. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Uses:	This product is intended for use as a positive control in Western Blot.
Dilutions:	Western Blot
TMW:	27.6 kDa
Concentrations:	1 mg/ml

This product is manufactured by and sold under license from OriGene Technologies and its use is limited solely for research purposes.

Buffer:	This product is provided in modified RIPA buffer.
Storage:	Store at -20C. Avoid freeze-thaw cycles.
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.