TRAF3IP2 Lysate

Applications: WB

Gene: TRAF3IP2 Purity: Protein

Specificity:	Homo sapiens TRAF3 interacting protein 2 (TRAF3IP2), transcript variant 2, mRNA.

Immunogen:	The lysate was created in HEK293T cells, using plasmid ID RC201106 and based on accession number NM_147686.

Type: Overexpression Tissue Condition: Normal

Life Stage: Adult Protein State: Native Sub-cellular Fraction: Whole

Entrez:	10758 (Human)
Swiss Prot:	NM_147686 (Human)
Related Genes:	NFKB1, NFKB1, TNF, NFKB1, IL17A, TRAF6, JUN, TRAF6, TRAF6, JUN, GUSB, ACT1, CCL4, ACT2, TNF, CD40, FOS, FOSB, CD40, JUND, JUNB, CD40, GUSB, NAT1, NAT1, SLC25A4, NAA15, TNFSF13B, IKBKB, CD40LG, MAPK8, MAPK8, IL17RA, CD40LG, MAPK8, RFC2, CD40LG, LOC222344, IL1B, IKBKE

This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens, inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Two alternative transcripts encoding different proteins have been identified. A third transcript, which does not encode a protein and is transcribed in the opposite orientation, has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts, suggesting it has a regulatory role in the expression of this gene. [provided by RefSeq]. Transcript Variant: This variant (2) lacks an alternate in-frame exon, compared to variant 1. Isoform 2 has a shorter and distinct N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Uses:	This product is intended for use as a positive control in Western Blot.
Dilutions:	Western Blot
TMW:	63.4 kDa
Concentrations:	1 mg/ml

This product is manufactured by and sold under license from OriGene Technologies and its use is limited solely for research purposes.

Buffer:	This product is provided in modified RIPA buffer.
Storage:	Store at -20C. Avoid freeze-thaw cycles.
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.