Activin A Receptor Type II-like 1 Lysate

Applications: WB

Gene: ACVRL1 Purity: Protein

Specificity:	Homo sapiens activin A receptor type II-like 1 (ACVRL1), transcript variant 1, mRNA.

Immunogen:	The lysate was created in HEK293T cells, using plasmid ID RC206568 and based on accession number NM_000020.

Type: Overexpression Tissue Condition: Normal

Life Stage: Adult Protein State: Native Sub-cellular Fraction: Whole

Entrez:	94 (Human)
Swiss Prot:	NM_000020 (Human)
Related Genes:	ENG, ENG, ENG, TGFBR1, TGFBR1, SLPI, ALK, ALK, ALK, TGFB1, BMPR2, SMAD1, TGFB1, GARS, SMAD1, SMAD2, SMAD1, VEGFA, VEGFA, VEGFA, BMPR2, TNFRSF8, TNFRSF8, SMAD2, SMAD2, TNFRSF8, BMPR2, ACVR1, SMAD4, SMAD4, SMAD4, TGFBR2, TGFBR2, INHBA, GDF2, INHBB, ID1, ID1, SMAD5, MS4A1

This gene encodes a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The encoded protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. [provided by RefSeq]. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same isoform. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Uses:	This product is intended for use as a positive control in Western Blot.
Dilutions:	Western Blot
TMW:	55.9 kDa
Concentrations:	1 mg/ml

This product is manufactured by and sold under license from OriGene Technologies and its use is limited solely for research purposes.

Buffer:	This product is provided in modified RIPA buffer.
Storage:	Store at -20C. Avoid freeze-thaw cycles.
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.