ACTR1A Lysate

Applications: WB

Gene: ACTR1A Purity: Protein

Specificity:	Homo sapiens ARP1 actin-related protein 1 homolog A, centractin alpha (yeast) (ACTR1A), mRNA.

Immunogen:	The lysate was created in HEK293T cells, using plasmid ID RC200738 and based on accession number NM_005736.

Type: Overexpression Tissue Condition: Normal

Life Stage: Adult Protein State: Native Sub-cellular Fraction: Whole

Entrez:	10121 (Human)
Swiss Prot:	NM_005736 (Human)
Related Genes:	ACTL6B, DCTN1, NR2F1, NR2F2, NR2F2, ABL1, AKAP5, ANPEP, CHAF1A, ANPEP, NR2F2, RAB3GAP2, CTR9, PIK3R4, ARFRP1, ANGPTL2, NR2F1, ACTR2, ACTR2, ANGPTL2, ACTR2, ACTR3B, AICDA, AICDA, RERE, CRISP1, RERE, RERE, MANF, VCSA1, ANGPTL6, DCTN2, SQSTM1, NUP62, KHDRBS1, GTF2H1, KHDRBS1, DCTN4, SQSTM1, IGF2BP2

This gene encodes a 42.6 kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 8-13 copies per dynactin molecule, and is the most abundant molecule in the dynactin complex. It is an actin-related protein, and is approximately 60% identical at the amino acid level to conventional actin. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Uses:	This product is intended for use as a positive control in Western Blot.
Dilutions:	Western Blot
TMW:	42.4 kDa
Concentrations:	1 mg/ml

This product is manufactured by and sold under license from OriGene Technologies and its use is limited solely for research purposes.

Buffer:	This product is provided in modified RIPA buffer.
Storage:	Store at -20C. Avoid freeze-thaw cycles.
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.