Actin Alpha 2 Smooth Muscle Lysate

Applications: WB

Gene: ACTA2 Purity: Protein

Specificity:	Homo sapiens actin, alpha 2, smooth muscle, aorta (ACTA2), transcript variant 2, mRNA.

Immunogen:	The lysate was created in HEK293T cells, using plasmid ID RC210641 and based on accession number NM_001613.

Type: Overexpression Tissue Condition: Normal

Life Stage: Adult Protein State: Native Sub-cellular Fraction: Whole

Entrez:	59 (Human)
Swiss Prot:	NM_001613 (Human)
Related Genes:	MYH7, DES, ACTG2, DES, DES, ACTC1, ACTC1, ACTB, ACTC1, NPPA, MYOD1, MYOD1, MYOD1, MYOG, MYOG, MYOG, TGFB1, NKX2-5, MYL1, NKX2-5, NKX2-5, MYH14, GJA1, MYL1, TNNT2, ACTA1, PTK7, SRF, ACTA1, PLN, PLN, TTN, CFB, TTN, ACTA1, PLN, LMNA, GATA4, TTN, CDKN1A

The protein encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Defects in this gene cause aortic aneurysm familial thoracic type 6. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Uses:	This product is intended for use as a positive control in Western Blot.
Dilutions:	Western Blot
TMW:	41.8 kDa
Concentrations:	1 mg/ml

This product is manufactured by and sold under license from OriGene Technologies and its use is limited solely for research purposes.

Buffer:	This product is provided in modified RIPA buffer.
Storage:	Store at -20C. Avoid freeze-thaw cycles.
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.