ACCN4 Lysate

Applications: WB

Gene: ACCN4 Purity: Protein

Specificity:	Homo sapiens amiloride-sensitive cation channel 4, pituitary (ACCN4), transcript variant 2, mRNA.

Immunogen:	The lysate was created in HEK293T cells, using plasmid ID RC203827 and based on accession number NM_182847.

Type: Overexpression Tissue Condition: Normal

Life Stage: Adult Protein State: Native Sub-cellular Fraction: Whole

Entrez:	55515 (Human)
Swiss Prot:	NM_182847 (Human)
Related Genes:	ACCN2, ACCN2, ACCN3, ACCN3, ACCN3, ACCN1, ACCN1, ACCN1, ACCN2, PCP2, SCNN1G, TNF, SCNN1A, PCP2, CASP1, PCP2, PICK1, RGS19, CASP1, TLR4, PICK1, GPSM1, GPSM2, GPSM1, GPSM1, TLR4, TLR4, CATSPER1, GPSM2, DRG1, CASP1, RIC8, SPP1, CATSPER1, SPP1, TNF, RGS19, PICK1, RGS19, SGPP1

This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. Alternative splicing at this locus results in two transcript variants encoding different isoforms. [provided by RefSeq]. Transcript Variant: This variant (2) is missing an inframe coding exon present in transcript variant 1. This results in a shorter isoform (2) lacking a 19 aa segment, compared to isoform 1.

Uses:	This product is intended for use as a positive control in Western Blot.
Dilutions:	Western Blot
TMW:	69.9 kDa
Concentrations:	1 mg/ml

This product is manufactured by and sold under license from OriGene Technologies and its use is limited solely for research purposes.

Buffer:	This product is provided in modified RIPA buffer.
Storage:	Store at -20C. Avoid freeze-thaw cycles.
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.