ACCN1 Lysate

Applications: WB

Gene: ACCN1 Purity: Protein

Specificity:	Homo sapiens amiloride-sensitive cation channel 1, neuronal (ACCN1), transcript variant 2, mRNA.

Immunogen:	The lysate was created in HEK293T cells, using plasmid ID RC210409 and based on accession number NM_001094.

Type: Overexpression Tissue Condition: Normal

Life Stage: Adult Protein State: Native Sub-cellular Fraction: Whole

Entrez:	40 (Human)
Swiss Prot:	NM_001094 (Human)
Related Genes:	ACCN2, ACCN2, SCNN1G, SCNN1A, ACCN3, ACCN3, ACCN3, ACCN2, PICK1, PICK1, PICK1, ACCN4, ACCN4, ACCN4, DRG1, ACCN5, STOM, BNC1, BDNF, DLG4, STOM, STOM, HSPA8, BNC1, BDNF, HSPA8, HSPA8, BDNF, BNC1, BNC2, FMR1, BNC2, BNC2, FMR1, TNFRSF11A, TNFRSF11A, CFTR, TRPV1, TRPV1, SCNN1B

This gene encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this gene may play a role in neurotransmission. In addition, a heteromeric association between this member and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium. Alternative splicing has been observed at this locus and two variants, encoding distinct isoforms, have been identified. [provided by RefSeq]. Transcript Variant: This variant (2) uses an alternate 5'-terminal exon, compared to variant 1, resulting in a shorter isoform (2) with a distinct N-terminus, compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Uses:	This product is intended for use as a positive control in Western Blot.
Dilutions:	Western Blot
TMW:	57.5 kDa
Concentrations:	1 mg/ml

This product is manufactured by and sold under license from OriGene Technologies and its use is limited solely for research purposes.

Buffer:	This product is provided in modified RIPA buffer.
Storage:	Store at -20C. Avoid freeze-thaw cycles.
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.