ACTH Antibody

Species: Ma, Hu Applications: IHC-Fr, IHC-P Clonality: Polyclonal

Gene: POMC Purity: Affinity purified Host: Rabbit

Specificity:	This reacts with human ACTH. This cross reacts with ACTH in a wide variety of mammalian species. Traces of contaminating antibodies have been removed by solid phase absorption.

Immunogen:	Synthetic human ACTH 1-24.
Localization:	Cytoplasmic, Secreted

Entrez:	5443 (Human)
Related Genes:	CRH, CRH, CRH, PRL, PRL, PRL, GH, AVP, AVP, AVP, INS, C1QL1, C1QL1, GNRHR, GH1, GH1, GGH, AGT, AGT, LHB, PLOD1, RT1-L, CACNB4, REN, REN, TRH, PBX1, MSX1, MSX2, TRH, IFNAR1, NLRP3, TNF, SST, SST, SST, NPY, NPY, NPY, TNF

ACTH occurs in cells of the anterior pituitary and in neurons in brain. It regulates the corticosteroid production in the adrenal cortex. Beta endorphin and Met enkephalin are endogenous opiates. MSH (melanocyte stimulating hormone) increases the pigmentation of skin by increasing melanin production in melanocytes.

Reactivity:	Cross-reacts with Human. Expected to cross-react with a wide range of other species due to sequence homology. Not yet tested in other species.

Uses:	This antibody may be diluted to a titer of 1:50-1:250 in an ABC method. We suggest an incubation period of 30 minutes at room temperature. Suitable for formalin/paraffin tissues.
Dilutions:	Immunohistochemistry-Paraffin , Immunohistochemistry-Frozen
Positive Controls:	1 positive controls

Buffer:	Constituents: Antiserum
Storage:	Store at 4C. Do not freeze.
Preservative:	No Preservative
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.