Angiotensin Converting Enzyme 1 Antibody (9B9)

Catalog#:	NB110-68278	This product is fully covered under guarantee+

Storage:	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer:	PBS, pH 7.4 containing 1% BSA
Preservative:	0.05% Sodium Azide

Purity:	Affinity purified
Host:	Mu
Clonality:	Monoclonal
Specificity:	ACE, no cross reactivity with testicular ACE.
Modification:	No
Clone:	9B9
Immunogen:	Human lung ACE

Entrez:	1636 (Human)
	24310 (Rat)
Related Genes:	1636

ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.

	Rt, Hu
reactivity:	This antibody is reactive against Human and Rat. Not yet tested in other species..

	IHC-Fr
Uses:	This antibody is useful for IHC for frozen sections.
Dilutions:	Immunohistochemistry-Frozen 1:500,
Positive Controls:	Angiotensin Converting Enzyme 1 Lysate (Angiotensin Converting Enzyme 1 Lysate (NBL1-07237)(0.1mg))

Publications:	Mizuiri, S. et al. A. J. Kidney Diseases. 1998; 31 (2): 301-307

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