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Clonality:	Monoclonal
Specificity:	ACE, no cross reactivity with testicular ACE.
Purity:	Affinity purified
Host:	Mouse

Immunogen:	Human lung ACE
Clone:	9B9

Entrez:	1636 (Human)
	24310 (Rat)

ACE converts angiotensin I to angiotensin II by release of the terminal His-Leu, this results in an increase of the vasoconstrictor activity of angiotensin. Also able to inactivate bradykinin, a potent vasodilatator. ACE exists in two forms, a 170KD somatic form and a 90KD germinal form. The somatic form is expressed by endothelial cells (especially those of lung capillaries and arterioles), epithelial cells (especially in proximal renal tubules and small intestine), by some neuronal cells and variably by some macrophages and T lymphocytes. The germinal form is expressed by spermatozoa.

	Rat, Human
Reactivity:	This antibody is reactive against Human and Rat. Not yet tested in other species..
*Note not all species have been tested for reactivity. Only those species listed have been tested. We cannot make any guarantees about additional reactivities or cross reactivities beyond those that have been tested. This antibody may or may not react with other species.

	IHC-Fr
Uses:	This antibody is useful for IHC for frozen sections.
Dilutions:	Immunohistochemistry-Frozen 1:500,
Positive Controls:	Angiotensin Converting Enzyme 1 Lysate (Angiotensin Converting Enzyme 1 Lysate (NBL1-07237)(0.1mg))

Storage:	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer:	PBS, pH 7.4 containing 1% BSA
Preservative:	0.05% Sodium Azide
Concentration:	0.2 mg/ml
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

1. Mizuiri, S. et al. A. J. Kidney Diseases. 1998; 31 (2): 301-307

AGT, REN, ANG, 2010317E24RIK, ATP2A2, AKR1C2, KRAS, HRAS1, MME, INS, AGTR1, AGTR1A, ID1, ATP8B2, ALB, AGTR1B, SLC33A1, DDR1, TENC1, ATM, TNF, ACE2, RAPGEF5, NOS3, AGXT, MGMT, TAC1, NPPA, EDN1, ACHE, DBP, GC, HSD17B4, MYBBP1A, UGT1A2, RXRT2, PLEKHM1, F2, NPPB, SERPINE1