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Clonality:	Polyclonal
Specificity:	ADAM 23
Purity:	Immunogen affinity purified
Host:	Chicken

Immunogen:	The immunogen for this antibody was a sequence from 72a.a. to 144a.a. from ADAM 23(a 832a.a. long protein)
Isotype:	IgY
Localization:	Nucleus.

Entrez:	8745 (Human)
Swiss Prot:	O75077 (Human)

ADAM23 is a non-catalytic metalloprotease-like protein. It is highly expressed in the brain, primarily in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole, and weakly expressed in the heart. 3 isoforms are produced by alternative splicing, alpha, beta and gamma. ADAM23 may play a role in cell-cell and cell-matrix interactions. May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein.

	Human
Reactivity:	This antibody is reactive against Human..
*Note not all species have been tested for reactivity. Only those species listed have been tested. We cannot make any guarantees about additional reactivities or cross reactivities beyond those that have been tested. This antibody may or may not react with other species.

	WB
Uses:	Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
Dilutions:	Western Blot

Storage:	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer:	Phosphate-Buffered Saline pH7.2
Preservative:	0.02% Sodium Azide
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

1. [1] Takada,H., Imoto,I., Tsuda,H., Nakanishi,Y., Ichikura,T., Mochizuki,H., Mitsufuji,S., Hosoda,F., Hirohashi,S., Ohki,M. , et al. ADAM23, a possible tumor suppressor gene, is frequently silenced in gastric cancers by homozygous deletion or aberrant promoter hypermethylation
2. [2] Costa,F.F., Colin,C., Shinjo,S.M., Zanata,S.M., Marie,S.K., Sogayar,M.C. Camargo,A.A. ADAM23 methylation expression analysis in brain tumors
3. [3] Brenberger,R., Wei,H., Zhang,S., Lei,S., Murage,J., Fisk,G.J., Li,Y., Xu,C., Fang,R., Guegler,K., Rao,M.S., Malam,R.,, et al. Transcriptome characterization elucidates signaling networks that control human ES cell growth differentiation

8 publications available on website

 

Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-ADAM23 )

61 Secondary Antibodies

ADAM11, ADAM22, ADAM28, CDKN2A, CCL22, MOGAT1, ADAM12, MST1, LMLN, LGI1, MSMB, TMPRSS13, KLK6, TFF2, CTLA4, ADAM9, NEFM, CACNA1S, METAP2, ADAM2, PRNP, CDH1, MAP2, CTGF, NOV, BMP2, MECP2, CREB1, FLT3L, FZR1, MTAP2, PRR14, KLF7, FLT3LG, FAP, CA1, PGR, ROBLD3, PRDX2, NKX2-9