Novus Biologicals, LLC
PO Box 802; Littleton, CO, 80160 USA
Phone: 303.730.1950 Fax: 303.730.1966

ADAM23 Antibody (NB100-75282)

ADAM23 Antibody

Catalog#:	NB100-75282	This product is fully covered under guarantee+

Storage:	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer:	Phosphate-Buffered Saline pH7.2
Preservative:	0.02% Sodium Azide

Purity:	Immunogen affinity purified
Host:	Ch
Clonality:	Polyclonal
Specificity:	ADAM 23
Modification:	No
Isotype:	IgY
Immunogen:	The immunogen for this antibody was a sequence from 72a.a. to 144a.a. from ADAM 23(a 832a.a. long protein)

Gene Symbol: ADAM23

Entrez:	8745 (Human)
Related Genes:	8745
Swiss Prot:	O75077 (Human)

Background:

ADAM23 is a non-catalytic metalloprotease-like protein. It is highly expressed in the brain, primarily in the amygdala, caudate nucleus, hypothalamus, thalamus, cerebral cortex and occipital pole, and weakly expressed in the heart. 3 isoforms are produced by alternative splicing, alpha, beta and gamma. ADAM23 may play a role in cell-cell and cell-matrix interactions. May play a role in cell-cell and cell-matrix interactions. This is a non-catalytic metalloprotease-like protein.

Species:

	Hu
reactivity:	This antibody is reactive against Human..

Applications:

	WB
Uses:	Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.
Dilutions:	Western Blot

Publications:	[1] Takada,H., Imoto,I., Tsuda,H., Nakanishi,Y., Ichikura,T., Mochizuki,H., Mitsufuji,S., Hosoda,F., Hirohashi,S., Ohki,M. , et al. ADAM23, a possible tumor suppressor gene, is frequently silenced in gastric cancers by homozygous deletion or aberrant promoter hypermethylation [2] Costa,F.F., Colin,C., Shinjo,S.M., Zanata,S.M., Marie,S.K., Sogayar,M.C. Camargo,A.A. ADAM23 methylation expression analysis in brain tumors [3] Brenberger,R., Wei,H., Zhang,S., Lei,S., Murage,J., Fisk,G.J., Li,Y., Xu,C., Fang,R., Guegler,K., Rao,M.S., Malam,R.,, et al. Transcriptome characterization elucidates signaling networks that control human ES cell growth differentiation 8 publications available on website

Publications:

[1] Takada,H., Imoto,I., Tsuda,H., Nakanishi,Y., Ichikura,T., Mochizuki,H., Mitsufuji,S., Hosoda,F., Hirohashi,S., Ohki,M. , et al. ADAM23, a possible tumor suppressor gene, is frequently silenced in gastric cancers by homozygous deletion or aberrant promoter hypermethylation [2] Costa,F.F., Colin,C., Shinjo,S.M., Zanata,S.M., Marie,S.K., Sogayar,M.C. Camargo,A.A. ADAM23 methylation expression analysis in brain tumors [3] Brenberger,R., Wei,H., Zhang,S., Lei,S., Murage,J., Fisk,G.J., Li,Y., Xu,C., Fang,R., Guegler,K., Rao,M.S., Malam,R.,, et al. Transcriptome characterization elucidates signaling networks that control human ES cell growth differentiation

8 publications available on website

Reviews

No reviews have been submitted for this product.

Working with ADAM23

Publications (8)

General:

[2] Costa,F.F., Colin,C., Shinjo,S.M., Zanata,S.M., Marie,S.K., Sogayar,M.C. Camargo,A.A. ADAM23 methylation expression analysis in brain tumors

[3] Brenberger,R., Wei,H., Zhang,S., Lei,S., Murage,J., Fisk,G.J., Li,Y., Xu,C., Fang,R., Guegler,K., Rao,M.S., Malam,R.,, et al. Transcriptome characterization elucidates signaling networks that control human ES cell growth differentiation

8 general publications available on website.

Images (1)

Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000, Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development. ( anti-ADAM23 )