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Clonality:	Polyclonal
Specificity:	The amino acid sequence used as immunogen is 100% homologous in human, 93% in dog and orangutan, 86% in chicken and 80% homologous in mouse and rat (isoform a). It is also 100% homologous in human ACP1 isoforms c and d. An uncharacterized 45 kD band is also seen and blocked by the immunizing peptide.
Purity:	Protein G purified
Host:	Rabbit

Immunogen:	A portion of amino acids 50-100 of human ACP1 was used as the immunogen.
Isotype:	IgG

Entrez:	52 (Human)

Official Gene Symbol: ACP1 Gen Bank Accession Number: NP_009030 Gene ID: 52 (Human) Gene Map Locus: 2p25 (Human) ACP1 (E.C 3.1.3.2) is a unique member of Phosphotyrosine Protein phosphotase family of proteins. It is ubiquitously expressed acid phosphotase functioning as an acid phosphotase and a protein tyrosine phosphotase. ACP1 has a cysteine-based catalytic mechanism and hydrolyzes protein tyrosine phosphate to protein tyrosine and orthophosphate. Reports suggest a functional role of ACP1 in TCR signaling and control of cell-cell adhesion through regulation of cytoskeletion assembly.

	Human
Reactivity:	Cross reacts with Human. .
*Note not all species have been tested for reactivity. Only those species listed have been tested. We cannot make any guarantees about additional reactivities or cross reactivities beyond those that have been tested. This antibody may or may not react with other species.

	WB
Uses:	Western Blot
Dilutions:	Western Blot 1-3 ug/ml
Positive Controls:	Whole Normal Liver Lysate (Whole Normal Liver Lysate (NB820-59232)(1.0mg)) ACP1 Lysate (ACP1 Lysate (NBL1-07250)(0.1mg))

Storage:	Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer:	PBS containing 0.2% gelatin
Preservative:	0.05% Sodium Azide
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

1. Wo,Y.Y., McCormack,A.L., Shabanowitz,J., Hunt,D.F., Davis,J.P., Mitchell,G.L. Van Etten,R.L. Sequencing, cloning, expression of human red cell-type acid phosphatase, a cytoplasmic phosphotyrosyl protein phosphatase J. Biol. Chem. 267 (15), 10856-10865 (1992)
2. Bottini et.al 277 (27) 24220-24224 (July 5, 2002)
3. Giannoni et.al JBC 278 (38) 36763-36776 (September 19, 2003)

3 publications available on website

 

Western Blot: ACP1 Antibody [NB100-56474] - Western blot analysis of ACP1 in the 1) absence and 2) presence of immunizing peptide in human liver lysate using NB100-56474 at 1 ug/ml.

2 Peptides and Proteins

7 Primary Antibodies

3 RNAi

123 Secondary Antibodies

PGM2, TRF, PGM1, ESD, HP, ADA, DLC1, HPR, GLO1, ABO, TF, PGD, F3, AK1, PTGDR, PHGDH, GPT, C3, DPAGT1, HR, SRC, OLFR48, RHD, RHCE, SGK3, ACP2, DARC, FUZ, ABCB1A, INS, PGPEP1, PGP, CA9, INSR, PTPN1, GRLF1, CAR2, GYPB, CA2, VPS33A