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PO Box 802; Littleton, CO, 80160 USA
Phone: 303.730.1950 Fax: 303.730.1966


ACSL5 Antibody (NB100-2918)

ACSL5 Antibody

Catalog#: NB100-2918 100% Guarantee
This product is fully covered under guarantee+
Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer: Tris-saline containing 0.02% Na azide [pH7.3] with 0.5% BSA
Preservative: 0.02% Sodium Azide
Purity: Immunogen affinity purified
Host: Gt
Clonality: Polyclonal
Specificity: ACSL5
Modification: No
Immunogen: C-RTQIDSLYEHIQDC TerminusNP_057318.2; NP_976313.1; NP_976314.1
Gene Symbol: ACSL5 
Entrez: 51703 (Human)
Related Genes: 51703
Swiss Prot: NP_057318.2; NP_976313.1; NP_976314.1 (Human)
Background:
The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in uterus and spleen, and in trace amounts in normal brain, but has markedly increased levels in malignant gliomas. This gene functions in mediating fatty acid-induced glioma cell growth. Three transcript variants encoding two different isoforms have been found for this gene.
Species:
Hu
reactivity: Human. .
Applications:
WB, PEP-ELISA
Uses: This antibody is useful for Peptide ELISA an Western Blot. Western Blot: Approx 75kDa band observed in human spleen lysates.
Dilutions: Peptide ELISA , Western Blot
Publications: Obermuller N, Keith M, Kopitz J, Autschbach F, Schirmacher P, Gassler N. Coeliac disease is associated with impaired expression of acyl-CoA-synthetase 5.Int J Colorectal Dis. 2005 Apr 5; [Epub ahead of print] pubmed: 15809837
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ACSL5 in Context

Research Areas related to ACSL5 (2):

Working with ACSL5

Publications (1)
General:

Obermuller N, Keith M, Kopitz J, Autschbach F, Schirmacher P, Gassler N. Coeliac disease is associated with impaired expression of acyl-CoA-synthetase 5.Int J Colorectal Dis. 2005 Apr 5; [Epub ahead of print] pubmed: 15809837


 
Images (1)
Western Blot: ACSL5 Antibody [NB100-2918] - NB100-2918 (1ug/ml) staining of Human Spleen lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. Western Blot: ACSL5 Antibody [NB100-2918] - NB100-2918 (1ug/ml) staining of Human Spleen lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.