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Summary:
Clonality: Polyclonal
Specificity: Please note, this product is one of a range of Investigative Grade antibodies, made against targets that have limited or no commercial antibodies available to them and for which there are no data on the expression of the protein in the range of common cell lines and tissues available to us. These antibodies are affinity purified using their peptide immunogen and are known to give low background staining in a western blot. However no additional claims are made for their ability to recognise native protein in any application.
Purity: Immunogen affinity purified
Host: Goat
Details:
Immunogen: Synthetic peptide: KISNSPEKPKVIQ representing the C-Terminus of the human protein (residues 491-503) according to NP_000011.
Isotype: IgG
Gene Symbol: ACVRL1 
Entrez: 94 (Human)
Swiss Prot: NP_000011. (Human)
Species:
Human
Reactivity: Human..
*Note not all species have been tested for reactivity. Only those species listed have been tested. We cannot make any guarantees about additional reactivities or cross reactivities beyond those that have been tested. This antibody may or may not react with other species.
Applications:
WB, PEP-ELISA
Uses: Peptide ELISA: antibody detection limit dilution 1:32000. Western Blot: Preliminary experiments gave no signal but low background in Human Lung and Liver extracts at up to 1ug/ml. We would appreciate any feedback from people in the field - have any results been reported with other antibodies/lysates?
Dilutions: Peptide ELISA 1:32000, Western Blot 1µg/ml
Positive Controls:
Packaging:
Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer: Tris saline containing [pH7.3] with 0.5% BSA
Preservative: 0.02% Sodium Azide
Concentration: 0.5 mg/ml
Limitations: This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Publications:
  1. Johnson DW et al. Mutations in the activin receptor-like kinase 1 gene in hereditary haemorrhagic telangiectasia type 2. Nat Genet 13:189-95 (1996).

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Research Areas related to Activin A Receptor Type II-like 1 (1):