Myeloperoxidase/MPO Antibody (8F4) 0.025 mg

Learn about our guarantee.
There are currently no images for Myeloperoxidase/MPO Antibody (NBP1-51148).

Every product we sell is backed by Novus' 100% Guarantee. If you have used this product, please submit your images and reviews to earn reward points. Be the first to review this product and earn double reward points.
Download Datasheet
See All Related

Ordering Information: NBP1-51148

  • Catalog Number
  • Displayed Format
  • Other Formats
  • Size(s)
    0.025 mg
  • Availability
  • Price

Myeloperoxidase/MPO Antibody (8F4) Summary

Species Mouse, Rat
Tested Applications Flow, IA, IHC, IHC-Fr
IgG purified
Guarantee Plus
All of our products are backed by our 100% guarantee to work for stated and predicted species and applications.
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Myeloperoxidase/MPO Antibody (8F4) Details

Purified mouse MPO from WEHI-3 cells

Species Reactivity

Please be aware that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional optimization may be required. Please contact Technical Support for more information.


  • Flow Cytometry 1:10-1:1000
  • Immunoassay
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1:10-1:500
Positive Controls
Other Available
Biotin Labeled NBP1-51149B
FITC Labeled NBP1-79141
Read Publications using
NBP1-51148 in the following applications:

    Contact Information

    Product PDFs

    Frequently Purchased Together


    Earn rewards points by submitting your review for Myeloperoxidase/MPO Antibody (NBP1-51148). Be the first to review this product and earn double rewards points!


    Myeloperoxidase/MPO Antibody (NBP1-51148) has been mentioned in at least 5 publications.
    Earn rewards if you have published using Myeloperoxidase/MPO Antibody (NBP1-51148).


    Positive control: Neutrophils isolated from digested infarcts Negative control: Lymphocytes isolated from digested infarcts

    Packaging, Storage & Formulations

    Store at 4C. Do not freeze.
    0.2 um filtered antibody solution in PBS, containing 0.1% bovine serum albumin.
    Unit Size
    0.025 mg
    0.1 mg/ml
    0.02% Sodium Azide
    This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.


    Gene Symbol MPO

    Alternate Names for Myeloperoxidase/MPO Antibody (8F4)

    • EC 1.11.1
    • EC
    • myeloperoxidase

    Related Products by Gene


    The monoclonal antibody 8F4 recognizes mouse myeloperoxidase (MPO). MPO is a glycoprotein produced as a single precursor, which is subsequently cleaved into a alpha and beta chain. In human the biologically active MPO is a 150kDa tetramer composed of 2 glycosylated alfa chains of 59-64 kDa and 2 beta chains of 14 kDa. MPO is stored in azurophilic granules of polymorphonuclear leukocytes and is rapidly released into the phagosome and extracellular space during inflammatory conditions.The enzyme catalyzes the conversion of chloride and hydrogen peroxide to hypochlorite, a potent oxidant, which functions in host defense against microorganisms. Involvement of MPO has been described in several human diseases, such as cardiovascular disease, airway inflammation, lung cancer, Alzheimer's disease and multiple sclerosis. A positive correlation between elevated MPO levels in serum and cardiovascular disease suggest an interesting role for MPO as an diagnostic marker, making it possible to identify patients at risk for future cardiac events. Furthermore, there are some autoimmune diseases, in which MPO is targeted by antineutrophil cytoplasm antibodies. Studies with MPO-knockout mice have shown an increased susceptibility to pneumonia following intratracheal infections. Moreover, MPO deficient mice are more susceptible to experimental autoimmune encephalitis, a T cell-dependent neuronal disease, and have an increased expression of arteriosclerotic plaques compared to wild-type mice.

    Reviews for Myeloperoxidase/MPO Antibody (NBP1-51148) (0)

    There are no reviews for Myeloperoxidase/MPO Antibody (NBP1-51148).
    By submitting a review earn points towards our Rewards Program.
    • 250 points for product review
    • 500 additional points for an image with your product review
    • Double points (500) if you are the first to review this product
    • Double points (1000) if you are the first to review this product with an image
    Have you used Myeloperoxidase/MPO Antibody (NBP1-51148)? Submit your review and earn rewards points which can be used for merchandise & discounts.
    Points can be redeemed for discounts and gift cards:
    $50/€35/£30/$50CAN Amazon Gift Card1000 Points
    Items ships for Free, please disregard any shipping charges.
    $50/€35/£30/$50CAN Off Purchase (credited after checkout)1000 Points
    Discount is removed from total when the order is processed. The discount will not appear in your shopping cart on check out.

    Publications for Myeloperoxidase/MPO Antibody (NBP1-51148) (5)

    Read what people are writing who have used Myeloperoxidase/MPO Antibody (NBP1-51148).

    Have you published using Myeloperoxidase/MPO Antibody (NBP1-51148)? Submit your review and earn rewards points which can be used for merchandise & discounts.

    Product General Protocols

    Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

    Ask a Scientist

    Submit your question on below.
    During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
    For immediate assistance during business hours M- F (excluding major holidays), please contact us.
    This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.

    FAQs for Myeloperoxidase/MPO (2)

    1. In the immunohistochemistry paraffin section protocol....the PBS buffer....should it be at certain pH?
      • For IHC application, different labs cites the pH of PBS buffer in the range of 7.1 - 7.6 but most commonly used pH is pH 7.4 (this is what we use in our lab). You may use this PBS (pH 7.4) for making permeablization buffer, antibody diluent buffers and for making wash buffer. For more on the protocol that we use in our lab and for IHC-P troubleshooting suggestions, you may visit: IHC-P Protocol and IHC-P Troubleshooting.
    2. I was wondering what does Format 7C mean as far as anitbodies go?
      • 7C is a fluorophore - it is useful for FLOW. The details of the fluor are (A=425, E=500)

    Bioinformatics Tool for Myeloperoxidase/MPO

    Discover related pathways, diseases and genes to Myeloperoxidase/MPO. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
    Bioinformatics Tool

    Research Areas for Myeloperoxidase/MPO

    Find related products by research area.

    Blogs on Myeloperoxidase/MPO

    There are no specific blogs for Myeloperoxidase/MPO, but you can read our latest blog posts.