M3II-21 reacts with an internal epitope of MRP3, a 190-200 kD transmembrane protein that is closely related to the multidrug resistance protein MRP1. M3II-21 was raised against a bacterial fusion protein of MRP3, containing amino acids 830-949 of the protein. M3II-21 does not cross-react with the human MDR1, MRP1, MRP2 or MRP5 gene products
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
M3II-21 has potential value for detection of MRP3-mediated drug-resistance in human tumor samples. Immunocytochemistry: use 1:20-1:50 dil. on acetone or formaldehyde fixed cytospin preparations. For immunohistochemistry: use 1:20 on acetone fixed frozen s
Dilutions:
Immunohistochemistry-Frozen, Western Blot, Flow Cytometry
Unit Size:
0.2 ml
Concentration:
This product is unpurified. Concentration is not relevant.
Packaging:
Storage:
Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles.
Preservative:
0.1% Sodium Azide
Limitations:
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.