METAP2 Lysate (NBL1-13019)

METAP2 Lysate

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METAP2 Lysate Summary:
Applications:WB
Gene:METAP2
Purity:Protein
Specificity:Homo sapiens methionyl aminopeptidase 2 (METAP2), mRNA.
 
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
METAP2 Lysate Details:
Immunogen:The lysate was created in HEK293T cells, using plasmid ID RC203809 and based on accession number NM_006838. The protein contains a C-terminal DDK tag.
Lysate Details:
Type: OverexpressionLife Stage: Adult
Protein State: Native Tissue Condition: Normal
Sub-cellular Fraction: Whole
Applications:
Uses:This product is intended for use as a positive control in Western Blot.
Dilutions:Western Blot
TMW:52.7 kDa
Unit Size:0.1 mg
Concentration:1.0 mg/ml
Notes:
This product is manufactured by and sold under license from OriGene Technologies and its use is limited solely for research purposes. Please note that “1 mg/ml” refers to the total protein concentration and that the specific protein concentration is not determined at this time.
Packaging:
Storage:Store at -80 °C. Avoid freeze-thaw cycles.
Buffer:This product is provided in modified RIPA buffer.
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: METAP2
Entrez10988 (Human)
Swiss ProtNM_006838 (Human)
 
Background:

This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

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