METAP2 Lysate (H00010988-T01)

METAP2 Lysate

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METAP2 Lysate Summary:
Applications:WB
Gene:METAP2
 
 
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
Lysate Details:
Type: OverexpressionLife Stage: Adult
Protein State: DenaturedTissue Condition: Normal
Sub-cellular Fraction: Whole
Applications:
Uses:This antibody is useful for Western Blot
Dilutions:Western Blot
Unit Size:0.1 ml
Concentration: mg/ml
Notes:
This product is produced by and distributed for Abnova, a company based in Taiwan.
Packaging:
Storage:Store at -80 °C. Avoid freeze-thaw cycles.
Buffer:In 50mM Tris-HCl, 2%SDS, 10% glycerol, 2% 2-mercaptoethanol, pH 6.8.
Preservative:No Preservative
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: METAP2
Swiss ProtNP_006829 (Human)
 
Background:

This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

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