METAP2 Antibody (H00010988-B01P)

METAP2 Antibody

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METAP2 Antibody Summary:
Species:Hu
Applications:ELISA, WB
Clonality:Polyclonal
Gene:METAP2
Purity:Protein A purified
Host:Mouse
Specificity:METAP2 - methionyl aminopeptidase 2,
 
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
METAP2 Antibody Details:
Immunogen:METAP2 (NP_006829.1, 1 a.a. ~ 478 a.a) full-length human protein.
Epitope:MAGVEEVAASGSHLNGDLDPDDREEGAAST AEEAAKKKRRKKKKSKGPSAAGEQEPDKES GASVDEVARQLERSALEDKERDEDDEDGDG DGDGATGKKKKKKKKKRGPKVQTDPPSVPI CDLYPNGVFPKGQECEYPPTQDGRTAAWRT TSEEKKALDQASEEIWNDFREAAEAHRQVR KYVMSWIKPGMTMIEICEKLEDCSRKLIKE NGLNAGLAFPTGCSLNNCAAHYTPNAGDTT VLQYDDICKIDFGTH
Species Reactivity:

Human.

Applications:
Uses:Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control.
Dilutions:Western Blot 1:500, ELISA
Unit Size:0.05 mg
Concentration:Please see the vial label for concentration.
Notes:
This product is produced by and distributed for Abnova, a company based in Taiwan.
Packaging:
Storage:Aliquot and store at -20 °C or -80 °C. Avoid freeze-thaw cycles.
Buffer:In 1x PBS, pH 7.2
Preservative:No Preservative
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: METAP2
Entrez10988 (Human)
Swiss ProtNP_006829.1 (Human)
 
Background:

This gene is a member of the methionyl aminopeptidase family and encodes a protein that binds 2 cobalt or manganese ions. This protein functions both by protecting the alpha subunit of eukaryotic initiation factor 2 from inhibitory phosphorylation and by removing the amino-terminal methionine residue from nascent protein. Increased expression of this gene is associated with various forms of cancer and the anti-cancer drugs fumagillin and ovalicin inhibit the protein by irreversibly binding to its active site. A pseudogene of this gene is located on chromosome 2. [provided by RefSeq]

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Working with METAP2

METAP2 Antibody Images (2)
Western Blot analysis of METAP2 expression in transfected 293T cell line by METAP2 MaxPab polyclonal antibody.

Lane 1: METAP2 transfected lysate(52.58 KDa).
Lane 2: Non-transfected lysate.
METAP2 MaxPab polyclonal antibody. Western Blot analysis of METAP2 expression in human liver.
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METAP2 in Context


Novus Explorer for METAP2 gene

Try our bioinformatic tool that shows the relationships between METAP2 and other genes, diseases, pathways and post-translational modifications.