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MEKK4 Antibody

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-55769
    • Availability
      Product Discontinued

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MEKK4 Antibody Summary

Immunogen
The antiserum was produced against synthesized peptide derived from human MAP3K4. The immunogen region is: C-terminal.
Specificity
MAP3K4 Antibody detects endogenous levels of total MAP3K4 protein.
Clonality
Polyclonal
Host
Rabbit
Gene
MAP3K4
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • ELISA 1:5000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:50-1:100

Reactivity Notes

Human,Mouse

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (without Mg2+ and Ca2+, pH 7.4), 0.15M NaCl and 50% Glycerol
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for MEKK4 Antibody

  • EC 2.7.11.25
  • FLJ42439
  • MAPKKK4yeast, homolog of
  • MEKK 4
  • mitogen-activated protein kinase kinase kinase 4

Background

MEK kinase 4 (MEKK4), also known as MTK1, is a Ser/Thr protein kinase belonging to the MAP kinase kinase kinase family (1). This protein contains a protein kinase catalytic domain at the C-terminus. The N-terminal, non-kinase domain may contain a regulatory domain. MEKK4 regulates p38 and JNK, butnot ERK pathway, through the phosphorylation of the MAP2Ks MKK3 and MKK6 and MKK4 and MKK7 respectively (1-2).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional MEKK4 Products

Array NBP1-55769

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Bioinformatics

Gene Symbol MAP3K4
Uniprot