MDR1 Antibody (NBP1-43787)
MDR1 Antibody (UIC2)
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anti-ABCB1 antibody, anti-ABC20 antibody, ABC20 antibody, PGY1 antibody, P gp antibody, P glycoprotein 1 antibody, Multidrug resistance protein 1 antibody, MDR1 antibody, MDR 1 antibody, GP170 antibody, CLCS antibody, CD243 antigen antibody, CD243 antibody, ATP binding cassette sub family B MDR/TAP member 1 antibody, anti-PGY1 antibody, anti-P-GP antibody, Anti-P gp antibody, anti-P glycoprotein 1 antibody
anti-P gp antibody
anti-PGY1 antibody, Anti-P glycoprotein 1 antibody, anti-Multidrug resistance protein 1 antibody, anti-MDR1 antibody, Anti-MDR 1 antibody, anti-GP170 antibody, anti-EC 3.6.3.44 antibody, anti-CLCS antibody, anti-CD243 antigen antibody, anti-CD243 antibody, Anti-ATP binding cassette sub family B MDR/TAP member 1 antibody, anti-ABCB1 antibody, anti-ABC20 antibody, ABCB1 antibody |
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MDR1 Antibody (UIC2) Summary: | | Gene: | ABCB1 |
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| Purity: | Affinity purified |
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| Host: | Mouse |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional MDR1 Products MDR1 Antibody (UIC2) Details: | Clone: | UIC2 |
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| Isotype: | IgG2a |
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| Immunogen: | The immunogen for this antibody was MDR1. |
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This antibody is reactive to Human. |
| Uses: | This UIC2 antibody has been pre-titrated and tested by flow cytometric analysis on the multidrug resistant cell line 8226 DOX40 and its parent line 8226/S. This can be used at 5 ul (0.5 ug)/per test. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. |
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| Dilutions: | Flow Cytometry |
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| Unit Size: | 25 tests (also available: 100 tests) |
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| Concentration: | 0.2 mg/ml |
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Packaging: | Storage: | Store at 4 °C. Do not freeze. |
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| Buffer: | Aqueous buffer (contains stabilizer if necessary) |
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| Preservative: | 0.09% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: This monoclonal antibody reacts with human Multidrug Resistant (MDR)-1, which is also known as P-glycoprotein (Pgp) and CD243. A 170-kDa transmembrane protein, MDR-1 is an ATP-dependent efflux pump for lipophilic compounds, including anti-cancer drugs. Expression of MDR-1 has been shown to correlate with multidrug resistance. In fact, tumor resistance to chemotherapy has been linked to MDR-1 expression in many cancers. MDR-1 is expressed in a variety of tissues, including the brain, kidney, liver, pancreas, and testes. Within the immune system, this molecule can be found on normal T, B, and natural killer cells, but not on monocytes. This antibody has been reported to inhibit MDR1-mediated efflux.
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Images (1) Reviews (0) Related Products (18) Exploring MDR1
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Working with MDR1
MDR1 Antibody (UIC2) Images (1)-Flow cytometry - FACS analysis-NBP1-43787-img0001.jpg "Flow cytometry / FACS analysis: P Glycoprotein Antibody (UIC2) [NBP1-43787] - Staining of the 8226/S (blue histogram) and 8226 DOX40 (purple histogram) cell lines with Mouse IgG2a k Isotype Control PE (left) or Anti-Human CD243 (ABCB1) PE (right). Total viable cells were used for analysis.") Flow cytometry / FACS analysis: P Glycoprotein Antibody (UIC2) [NBP1-43787] - Staining of the 8226/S (blue histogram) and 8226 DOX40 (purple histogram) cell lines with Mouse IgG2a k Isotype Control PE (left) or Anti-Human CD243 (ABCB1) PE (right). Total viable cells were used for analysis. |
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Jump to: Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPeptides and ProteinsPrimary Antibodies (10)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| MDR1 Antibody (C219) | NB600-1036 | Ca, Hu, Mk, Mu, Rt | ICC, IHC-Fr, IHC-P, IP, WB | | (6) | | | | MDR1 Antibody (PG-13) | NBP1-42581 | Hu | ICC, IF, IHC-Fr, IHC-P, IP, WB | | | | | | MDR1 Antibody (JSB-1) | NBP1-51768 | Ha, Mu(-), Rt(-) | FACS, IHC-Fr, IHC-P, WB | | | | | | MDR1 Antibody | NB100-80870 | Ca, Hu, Mk, Mu(-), Rt | ELISA, IHC-P, WB | (1) | | | | | MDR1 Antibody | NBP1-19787 | Hu, Mu, Rt | IF, IHC-P | (2) | | | | | ... and 5 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Mouse IgG Antibody [Biotin] | NB720-B | Mu | ELISA, IHC-P, WB | | | | | | Mouse IgG Antibody [HRP] | NB720-H | Mu | ELISA, ICC, IHC-P, WB | | | | | | Mouse IgG Antibody [Alkaline Phosphatase] | NB720-AP | Mu | ELISA, ICC, IHC-P, WB | | | | | | Mouse IgG Antibody [FITC] | NB720-F | Mu | ICC, IHC-P | | (2) | | | | Mouse IgG Antibody | NB120-7056 | Bv(-), Ch(-), Eq(-), Gp(-), Gt(-), Ha(-), Hu(-), Mu, Rb(-), Rt(-), Sh(-) | ELISA, IHC-P, IP, WB | | | | | | See All » |
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