We're moving to rndsystems.com. Come with us!

After August 17, 2026, Novus Biologicals products and services will no longer be available on this website; you will access all products and services on rndsystems.com. Create your R&D Systems online account today.

MDR1/ABCB1 Antibody (PG-13)

Images

 

Product Details

Summary
Product Discontinued
View other related MDR1/ABCB1 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-42581
    • Availability
      Product Discontinued

    Can't find what you are looking for? Use our Antibody Concierge Service & we will help you locate your antibody!

    Or feel free to contact us for alternative products.

MDR1/ABCB1 Antibody (PG-13) Summary

Immunogen
A mixture of human and hamster drug-resistant whole cells and crude plasma membranes.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ABCB1
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Frozen 1-2 ug/ml
  • Immunohistochemistry-Paraffin 1-2 ug/ml
  • Western Blot 0.5-1 ug/ml

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
1.2% Sodium Acetate and 0.2 mg BSA
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A or G purified
Reconstitution Instructions
Reconstitute with deionized water.

Alternate Names for MDR1/ABCB1 Antibody (PG-13)

  • ABC20
  • ABCB1
  • ABCB1B
  • ATP-binding cassette sub-family B member 1
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1
  • CD243 antigen
  • CD243
  • CLCS
  • colchicin sensitivity
  • doxorubicin resistance
  • EC 3.6.3
  • EC 3.6.3.44
  • GP170
  • IBD13
  • MDR1
  • MDR1MGC163296
  • multidrug resistance protein 1
  • P-glycoprotein 1
  • P-gp
  • PGY1
  • PGY1P-GP

Background

P Glycoprotein, the product of the MDR1 gene, is expressed in distinct non-malignant cells, typically cells with secretory and excretory functions. It is assumed to function as an ATP-dependent drug efflux pump with broad substrate specificity. The highest expression of P Glycoprotein has been observed in kidney (proximal tubules), liver (bile canaliculi), adrenal gland and intestine, suggesting that the primary role of P Glycoprotein is in the normal secretion of physiological metabolites and ingested chemicals into bile, urine and the lumen of the intestinal tract. Elevated levels of P Glycoprotein have also been reported in multidrug-resistant cell lines and in colon, endometrial, ovarian, and breast tumors, as well as in sarcomas and leukemias / lymphomas.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NB400-156
Species: Hu, Mu, Rt
Applications: CyTOF-ready, Dual ISH-IHC, ELISA, Flow, ICC/IF, IHC, IP, Simple Western, WB
NBP2-22124
Species: Hu, Mu, Pm
Applications: ELISA, Flow, ICC/IF, IHC,  IHC-P, WB
NBP1-69023
Species: Mu
Applications: WB
NBP3-24587
Species: Hu
Applications: ICC/IF, IHC,  IHC-P, WB
NB100-556
Species: Hu
Applications: IP, WB
NBP2-37502
Species: Hu
Applications: CyTOF-ready, ELISA, Flow, ICC/IF, IHC,  IHC-P, WB
NBP3-41339
Species: Hu, Mu, Rt
Applications: IHC,  IHC-P, WB
NBP2-38160
Species: Hu
Applications: ICC/IF, IHC,  IHC-P
NBP3-46186
Species: Hu, Mu, Rt
Applications: ELISA, IHC, IP, WB
AF6278
Species: Hu, Mu
Applications: WB
NBP1-82820
Species: Hu
Applications: ICC/IF, IHC,  IHC-P, Simple Western, WB
NBP1-76670
Species: Hu, Rt
Applications: ELISA, IHC,  IHC-P, WB
NBP2-30876
Species: Hu
Applications: IHC,  IHC-P
PP-H4417-00
Species: Hu
Applications: DirELISA, IP, WB
NBP1-68885
Species: Hu
Applications: IHC, WB
NB200-103
Species: Hu, Mu, Rt, Xp(-), Ye
Applications: CyTOF-ready, ELISA, Flow-IC, Flow, ICC/IF, IHC, IHC-Fr,  IHC-P, IP, WB
NBP2-37923
Species: Hu
Applications: ICC/IF, IHC,  IHC-P
NB100-64808
Species: Hu
Applications: ELISA, Flow, ICC/IF, IHC, IHC-Fr, IP, WB

Publications for MDR1/ABCB1 Antibody (NBP1-42581) (0)

There are no publications for MDR1/ABCB1 Antibody (NBP1-42581).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for MDR1/ABCB1 Antibody (NBP1-42581) (0)

There are no reviews for MDR1/ABCB1 Antibody (NBP1-42581). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for MDR1/ABCB1 Antibody (NBP1-42581) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional MDR1/ABCB1 Products

Research Areas for MDR1/ABCB1 Antibody (NBP1-42581)

Find related products by research area.

Blogs on MDR1/ABCB1

There are no specific blogs for MDR1/ABCB1, but you can read our latest blog posts.

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our MDR1/ABCB1 Antibody (PG-13) and receive a gift card or discount.

Bioinformatics

Gene Symbol ABCB1