MDR1 Antibody (NB600-1036)
MDR1 Antibody (C219)
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anti-ABC20 antibody, anti-PGY1 antibody, Anti-P gp antibody, Anti-P glycoprotein 1 antibody, anti-Multidrug resistance protein 1 antibody, anti-MDR1 antibody, Anti-MDR 1 antibody, anti-GP170 antibody, anti-CLCS antibody, anti-CD243 antigen antibody, anti-CD243 antibody, Anti-ATP binding cassette sub family B MDR/TAP member 1 antibody, anti-ABCB1 antibody, |
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MDR1 Antibody (C219) Summary: | | Gene: | ABCB1 |
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| Purity: | Protein G purified |
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| Host: | Mouse |
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| | Specificity: | Analysis of p-glycoprotein expression in skeletal and cardiac muscle revealed that C219 cross reacts with a 200kDa protein that migrates in the same position as myosin. C219 has also been reported to detect the 185kDa c-erbB2 protein (Liu, et al 1997). Care should be taken in the interpretation of true positive P-glycoprotein expression when using myosin-containing tissues or tissues known to have p185 c-erbB2 expression. |
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| Publications: | Antibody has been mentioned in at least 2 Publications. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional MDR1 Products MDR1 Antibody (C219) Details: | Clone: | C219 |
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| Isotype: | IgG1 |
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| Immunogen: | SDS-solubilized plasma membranes of a multidrug resistant Chinese hamster ovary (CHO) cell line and a human cell line. |
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| Localization: | Cell Membrane; Integral membrane protein |
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| Epitope: | This antibody recognizes an internal, highly conserved amino acid sequence: VQEALD and VQAALD, corresponding to the C-terminal and N-terminal regions, respectively, found in both MDR1 and MDR3 isoforms of P Glycoprotein. The specific binding of the clone |
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Cross-reacts with Human and Rat. Expected to cross-react with wide range of Mammals due to highly conserved epitope sequence. Not yet tested in other species. |
| Uses: | IHC-P: Use for Biotin-based detection systems. Sections should be pre-treated with an antigen unmasking solution. Predicted molecular weight: 141 kDa. *Human liver (positive staining detected along luminal surfaces of bile canaliculi) or human colon (positive staining localized to luminal surface of secretaory epithelium) can be used as positive controls for IHC. **For optimal staining, the primary antibody should be incubated 60 minutes at room temperature. NOTE: Optimal dilutions/concentrations should be determined by the end user. |
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| Dilutions: | Immunocytochemistry, Immunohistochemistry-Frozen 1/25, Immunohistochemistry-Paraffin 1/25, Immunoprecipitation, Western Blot |
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| Unit Size: | 0.25 ml |
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| Concentration: | Please see the vial label for concentration. |
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| Positive Controls: | 2 Positive Controls |
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Packaging: | Storage: | Store at 4 °C. Do not freeze. |
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| Buffer: | 1% BSA, 0.01M PBS |
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| Preservative: | 0.1% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Reviews (0) Related Products (18) Working with MDR1
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Working with MDR1
MDR1 Antibody (C219) Images (0)
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Publications (2)
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Jump to: Positive Controls, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPositive Controls| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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Other Positive Controls- Human liver (positive staining detected along luminal surfaces of bile canaliculi)
- human colon (positive staining localized to luminal surface of secretaory epithelium)
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Peptides and ProteinsPrimary Antibodies (10)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| MDR1 Antibody (PG-13) | NBP1-42581 | Hu | ICC, IF, IHC-Fr, IHC-P, IP, WB | | | | | | MDR1 Antibody (JSB-1) | NBP1-51768 | Ha, Mu(-), Rt(-) | FACS, IHC-Fr, IHC-P, WB | | | | | | MDR1 Antibody | NBP1-90291 | Hu | IF, IHC-P, WB | (1) | | | | | MDR1 Antibody | NB100-80870 | Ca, Hu, Mk, Mu(-), Rt | ELISA, IHC-P, WB | (1) | | | | | MDR1 Antibody | NBP1-19787 | Hu, Mu, Rt | IF, IHC-P | (2) | | | | | ... and 5 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Mouse IgG Antibody [Biotin] | NB720-B | Mu | ELISA, IHC-P, WB | | | | | | Mouse IgG Antibody [HRP] | NB720-H | Mu | ELISA, ICC, IHC-P, WB | | | | | | Mouse IgG Antibody [Alkaline Phosphatase] | NB720-AP | Mu | ELISA, ICC, IHC-P, WB | | | | | | Mouse IgG Antibody [FITC] | NB720-F | Mu | ICC, IHC-P | | (2) | | | | Mouse IgG Antibody | NB120-7056 | Bv(-), Ch(-), Eq(-), Gp(-), Gt(-), Ha(-), Hu(-), Mu, Rb(-), Rt(-), Sh(-) | ELISA, IHC-P, IP, WB | | | | | | See All » |
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