ABC20 antibody, PGY1 antibody, P gp antibody, P glycoprotein 1 antibody, Multidrug resistance protein 1 antibody, MDR1 antibody, MDR 1 antibody, GP170 antibody, CLCS antibody, CD243 antigen antibody, CD243 antibody, ATP binding cassette sub family B MDR/TAP member 1 antibody, ABCB1 antibody
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
Colchicine resistant viable Chinese Hamster Ovary.
Localization:
Cell Membrane
Species Reactivity:
Cross-reacts with Armenian Hamster. Does not cross-react with Human.
Applications:
Uses:
Flow Cytometry assay dependent.Immunofluorescence: assay dependent.Western blot: use at a concentration of 1 - 2ug/ml for 2 hours at RT.Immunohistochemistry (frozen sections):assay dependent.Not tested in other applications.Optimal dilutions / concentrations should be determined by the end user.By Western blot, this antibody detects a band of ~ 170 kDa, which corresponds to the predicted molecular weight of P glycoprotein.
Dilutions:
Flow Cytometry ,
immunofluorescence ,
Western Blot ,
Immunohistochemistry-Frozen
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Multi Drug Resistance (MDR) associated p-glycoprotein (p170) causes resistance to various drugs in a number of cancer patients. It exists in a soluble and membrane associated form. Soluble P glycoprotein is detected in extracellular fluids of cancer patients such as malignant ascites and serum. The MW of soluble P glycoprotein is the same as that of membrane bound P glycoprotein.