MCP1 Antibody (NB110-2000)
MCP1 Antibody
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Distributor Data...
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anti-Monocyte Chemoattracctant Protein 1 antibody |
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MCP1 Antibody Summary: | | Gene: | CCL2 |
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| Purity: | Protein A purified |
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| Host: | Rabbit |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional MCP1 Products MCP1 Antibody Details: | Isotype: | IgG |
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| Immunogen: | E. coli expressed rat MCP1. |
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| Localization: | Secreted |
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Cross-reacts with Mouse JE and Rat MCP-1. |
| Uses: | This antibody is useful in Immunohistochemistry and Western Blot. |
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| Dilutions: | Western Blot 1/2000,
Immunohistochemistry-Paraffin 1/100 |
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| Unit Size: | 0.1 mg |
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| Concentration: | 1.0 mg/ml |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | PBS |
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| Preservative: | 0.1% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: Rat MCP-1/JE (monocyte chemoattracctant protein-1) is a 148-amino acid CC chemokine with a NH2-terminal sequence of 29 residues as a signal sequence. It was originally cloned from Con A-stimulated rat spleen cDNA library1. This rat MCP-1/JE is 49-amino acid longer than human MCP-1 at 3'-end. This 3'-end is a serine and threonine rich zone, which is probably responsible for the extensive O-glycosylation and explains for the higher molecular weight (25 kDa)2. In vitro, MCP-1/JE is chemotactic for monocytes as well as lymphocytes and basophils, but not for neutrophils. MCP-1/JE is produced by a wide range of cell types as a reaction to diverse inflammatory stimuli3.
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Images (1) Reviews (0) Related Products (62) Exploring MCP1 Working with MCP1
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Working with MCP1
MCP1 Antibody Images (1) Rat MCP-1 detected in RAW cells stimulated with LPS for 15 hrs. 1, lysate: 2, supernatant |
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Publications (3)MCP1 Antibody Background References:- Haelens, A. et al. (1996) Leukocyte migration activation by murine chemokines. Immunobiol 195:499-521
- Rollins, B.J. et al (1989) The human homolog of the JE gene encodes a monocyte secretory protein. Mol Cell Biol 9:4687
more... - Yoshimura,T. et al. (1991) Molecular cloning of rat monocyte chemoattractant protein-1 (MCP-1) its expression in rat spleen cells tumor cell lines. Biochem. Biophys. Res. Commun. 174:504-509
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Jump to: Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsLysates (2)Peptides and ProteinsPrimary Antibodies (40)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| MCP1 Antibody | NBP1-07035 | Hu, Mu, Rt | WB | (1) | (3) | | | | MCP1 Antibody | NBP1-07034 | Hu, Mu, Rt | WB | (1) | (3) | | | | MCP1 Antibody | NBP1-07034PEP | Hu, Mu, Rt | WB | | (3) | | | | MCP1 Antibody | 20530002 | Hu | ELISA, IHC-P | (2) | | | | | MCP1 Antibody (24822.11) | NB120-10390 | Hu | B/N, ELISA, IB, IHC-Fr, IHC-P | | (4) | | | | ... and 35 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Rabbit IgG Antibody [HRP] | NB730-H | Rb | ELISA, ICC, IHC-P, WB | | (5) | | | | Rabbit IgG Antibody [FITC] | NB730-F | Rb | ICC, IHC-P | | (1) | | | | Rabbit IgG Antibody [Biotin] | NB730-B | Rb | ELISA, ICC, IHC-P, WB | | | | | | Rabbit IgG, H/L Chains Antibody [DyLight 488] | NBP1-72944 | Rb | FLISA, IF, WB | (3) | | | | | Rabbit IgG Antibody [Alkaline Phosphatase] | NB730-AP | Rb | ELISA, ICC, IHC-P, WB | | (1) | | | | See All » |
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