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CCL2/MCP1 Antibody

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Product Details

Summary
Product Discontinued
View other related CCL2/MCP1 Primary Antibodies

Order Details


    • Catalog Number
      NB110-2000
    • Availability
      Product Discontinued

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CCL2/MCP1 Antibody Summary

Immunogen
E. coli expressed rat MCP1.
Localization
Secreted
Specificity
Reacts to mouse JE and rat MCP1
Clonality
Polyclonal
Host
Rabbit
Gene
CCL2
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot 1/2000
Publications
Read Publications using
NB110-2000 in the following applications:

  • IHC-P
    1 publication
  • WB
    1 publication

Reactivity Notes

Cross-reacts with Mouse JE and Rat MCP-1.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Purity
Protein A purified

Alternate Names for CCL2/MCP1 Antibody

  • C-C motif chemokine 2
  • chemokine (C-C motif) ligand 2
  • GDCF-2
  • HC11Monocyte secretory protein JE
  • MCAFMonocyte chemotactic and activating factor
  • MCP1 Monocyte chemotactic protein 1
  • MCP-1 Small-inducible cytokine A2
  • MGC9434
  • Monocyte chemoattractant protein 1
  • monocyte chemoattractant protein-1
  • SCYA2HSMCR30
  • small inducible cytokine A2 (monocyte chemotactic protein 1, homologous tomouse Sig-je)
  • small inducible cytokine subfamily A (Cys-Cys), member 2
  • SMC-CF

Background

Rat MCP-1/JE (monocyte chemoattracctant protein-1) is a 148-amino acid CC chemokine with a NH2-terminal sequence of 29 residues as a signal sequence. It was originally cloned from Con A-stimulated rat spleen cDNA library1. This rat MCP-1/JE is 49-amino acid longer than human MCP-1 at 3'-end. This 3'-end is a serine and threonine rich zone, which is probably responsible for the extensive O-glycosylation and explains for the higher molecular weight (25 kDa)2. In vitro, MCP-1/JE is chemotactic for monocytes as well as lymphocytes and basophils, but not for neutrophils. MCP-1/JE is produced by a wide range of cell types as a reaction to diverse inflammatory stimuli3.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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CCL2/MCP1 Antibody
NB110-2000
CCL2/MCP1 Antibody
Species: Mu, Rt
Applications: WB

Publications for CCL2/MCP1 Antibody (NB110-2000)(2)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 2 applications: IHC-P, WB.


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IHC-P
(1)
WB
(1)
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Mouse
(2)
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Blogs on CCL2/MCP1.

Check out the latest blog posts on CCL2/MCP1.
MCP-1 - chemoattractant protein involed in monocyte migration and infiltration
Monocyte chemotractant protein-1 (MCP-1), also known as CCL2, is a key chemokine involved in the migration of monocytes and macrophages to sites of active inflammation. It is a member of the C-C/beta family of cytokines, characterized by the Cys-C...  Read full blog post.

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Bioinformatics

Gene Symbol CCL2
Entrez
Uniprot