MCP1 Antibody (NB120-10390)

MCP1 Antibody (24822.11)

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MCP1 Antibody (24822.11) Summary:
Species:Hu
Applications:B/N, ELISA, IB, IHC-Fr, IHC-P
Clonality:Monoclonal
Gene:CCL2
Purity:Protein A purified
Host:Mouse
Specificity:The will neutralize the biological activity of recombinant human MCP-1.This does not exhibit cross-reactivity with recombinant human RANTES, recombinant human MIP-1á, or recombinant mouse MIP-1á..
Publications:Antibody has at least 4 Background References.
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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MCP1 Antibody (24822.11) Details:
Clone:24822.11
Isotype:IgG1
Immunogen:Recombinant human MCP-1 (rhMCP-1), expressed in E. coli.
Localization:Secreted
Species Reactivity:

Cross-reacts with Human.Not yet tested in other species.

Applications:
Uses:Neut: Use at a concentration of 0.1 ug/ml. Human MCP1 is tested for its ability to neutralize the chemoattractant activity of rhMCP1 for human monocytes. The ND50 of the antibody is defined as the concentration of antibody resulting in a one-half maximal inhibition of bioactivity of rhMCP1 that was present at a concentration just high enough to elicit a maximum response. In this bioassay, rhMCP1 was preincubated with various dilutions of the antibody for 1 hour at 37
Dilutions:Immunoblotting, Neutralizing, Immunohistochemistry Frozen, Immunohistochemistry-Paraffin, ELISA
Unit Size:0.1 mg
Concentration:0.5 mg/ml
Packaging:
Storage:Store at -20 °C. Avoid freeze-thaw cycles.
Buffer:Preservative: None Constituents: PBS
Preservative:5% Trehalose
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: CCL2
Entrez6347 (Human)
 
Background:

This chemotactic factor attracts monocytes and basophils but not neutrophils or eosinophils and augments monocyte anti-tumor activity. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. It may be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis.

Jump to: Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies

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RNAi (1)
NameCatalog#ReactivityApplicationsImagesPublicationsReviews
MCP1 RNAiH00006347-R02Hu(1)(4)

Secondary Antibodies
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Mouse IgG Antibody [Biotin]NB720-BMuELISA, IHC-P, WB

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Mouse IgG Antibody [Alkaline Phosphatase]NB720-APMuELISA, ICC, IHC-P, WB

Mouse IgG Antibody [FITC]NB720-FMuICC, IHC-P(2)

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Jump to: Novus Explorer, Research Areas

MCP1 in Context


Research Areas related to MCP1 (5):
Novus Explorer for MCP1 gene

Try our bioinformatic tool that shows the relationships between CCL2 and other genes, diseases, pathways and post-translational modifications.