Lck Antibody (NB110-57284)
Lck Antibody (Y123)
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anti-Lck p56 antibody, anti-YT16 antibody, anti-YT 16 antibody, anti-T lymphocyte specific protein tyrosine kinase p56lck antibody, anti-T cell specific protein tyrosine kinase antibody, anti-Protooncogene tyrosine protein kinase LCK antibody, anti-Proto oncogene tyrosine protein kinase LCK antibody, anti-pp58lck antibody, anti-pp58 lck antibody, anti-p56lck antibody, anti-p56(LSTRA) protein tyrosine kinase antibody, anti-P56 LCK antibody, anti-Oncogene lck antibody, anti-Membrane associated protein tyrosine kinase antibody, anti-Lymphocyte Specific Protein Tyrosine Kinase antibody, anti-Lymphocyte cell specific protein tyrosine kinase antibody, Anti-LSK antibody |
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Lck Antibody (Y123) Summary: | | Gene: | LCK |
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| Purity: | IgG purified |
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| Host: | Rabbit |
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| | Specificity: | The antibody does not cross-react with other SRC family member. |
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| Publications: | Antibody has at least 1 Background Reference. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional Lck Products Lck Antibody (Y123) Details: | Clone: | Y123 |
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| Isotype: | IgG |
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| Immunogen: | A synthetic peptide corresponding to residues before SH3 domain of human Lck was used as immunogen. |
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Reacts in Human. Does not react to Mouse or Rat. |
| Uses: | This product is useful for: Western Blot, Immunohistochemistry-Paraffin, Immunocytochemistry, Immunoprecipitation, Flow Cytometry. In Western blot this antibody detects a band at approximately 56kDa. |
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| Dilutions: | Western Blot 1:1000, Immunohistochemistry-Paraffin 1:250-500, Immunocytochemistry 1:100, Immunoprecipitation 1:200, Flow Cytometry 1:20 |
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| TMW: | 56 kDa |
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| Unit Size: | 0.1 ml |
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| Concentration: | Please see the vial label for concentration. |
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| Positive Controls: | 1 Positive Controls |
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Packaging: | Storage: | Store at -20 °C. Avoid freeze-thaw cycles. |
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| Buffer: | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, and 0.05% BSA. |
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| Preservative: | 0.01% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: The human T-cell or lymphocyte specific gene Lck/p56 is a member of the Src family of non-receptors tyrosine kinase. Mostly expressed in T cells, Lck has been shown to be critical for the normal development of T lymphocytes (1). Additionally, the N-terminal region of the tyrosine kinase Lck interacts with the cytoplasmic domains of CD4 and CD8 (2). Autophosphorylation at Tyr-394 appears to be required for maximum catalytic activity (3) but it can also be suppressed by phosphorylation of the carboxyl-terminal tyrosine Tyr-505 (4).
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Images (2) Reviews (0) Related Products (48) Exploring Lck Working with Lck
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Jump to: Publications, Images, Protocols/Procedures, Ask a Question
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Working with Lck
Lck Antibody (Y123) Images (2) Immunohistochemistry: Lck/p56 Antibody (Y123) [NB110-57284] - Immunohistochemical analysis of paraffin-embedded human lymphoma using anti-Lck/p56 (catalog #110-57284). |  Western Blot: Lck/p56 Antibody (Y123) [NB110-57284] - Western blot analysis on Jurkat cell lysate using anti-Lck/p56 (catalog #110-57284), dilution 1:1,000. |
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Publications (1)Lck Antibody (Y123) Background References:- Rudd, C. E., Trevillyan, J. M., Dasgupta, J. D., Wong, L. L., Schlossman, S. F. (1988) Proc. Natl. Acad. Sci., U. S. A. 85, 5190
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Jump to: Positive Controls, Antibody Pairs, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsPositive ControlsAntibody Pairs (2)Lysates (2)Peptides and ProteinsPrimary Antibodies (21)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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RNAi (2)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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