LKB1 Antibody (NBP1-19951)
LKB1 [p Ser428] Antibody
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Distributor Data...
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anti-Serine/threonine-protein kinase 11 antibody, anti-STK11 antibody, anti-Serine/threonine-protein kinase LKB1 antibody, anti-Renal carcinoma antigen NY-REN-19 antibody, anti-PJS antibody, anti-LKB1 antibody, |
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LKB1 [p Ser428] Antibody Summary: | | Gene: | STK11 |
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| Purity: | Affinity purified |
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| Host: | Rabbit |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional LKB1 Products LKB1 [p Ser428] Antibody Details: | Immunogen: | Synthetic peptide corresponing to the residues surrounding Serine 428 of human p-LKB1 |
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| Modification: | p Ser428 |
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| Uses: | This antibody is useful for Western Blot and Immunohistochemistry. Western blot analysis of p-LKB1 (S428) antibody in extracts from CV-1 forsklin cells. Immunohistochemistry analyzes of p-LKB1 (S428) antibody in paraffin-embedded human breast carcinoma tissue. This antibody is also useful for Immunofluorescence. Purity is > 95% (by SDS-PAGE). |
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| Dilutions: | Immunofluorescence 1:50-1:200, Immunohistochemistry-Paraffin 1:50-1:200, Western Blot 1:500-1:1000 |
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| Unit Size: | 0.1 mg |
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| Concentration: | 1.0 mg/ml |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | Phosphate buffered saline (PBS), approx. pH 7.2. |
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| Preservative: | 15mM Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: Peutz-Jeghers syndrome (PJS) is a rare hereditary disease characterized by melanocytic macules lips, gastrointestinal hamartomatous polyps and an increased risk for many classes of cancer. LKB1 (also designated STK11 and PJS) has been identified as the gene mutated in PJS. LKB1 is a 433 amino acid Serine/Threonine kinase with strong homology to the Xenopus cytoplasmic protein kinase XEEK1 and weaker similarity to many other protein kinases. LKB1 is ubiquitously expressed and many frameshift, deletion and splicing mutations have been identified in PJS patients. Despite the increased risk of cancer for PJS patients, LKB1 does not appear to play a major role in colorectal, testicular or breast cancers.
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Images (2) Reviews (0) Related Products (33) Exploring LKB1
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Working with LKB1
LKB1 [p Ser428] Antibody Images (2) Immunohistochemistry: LKB1 [phospho Ser428] Antibody [NBP1-19951] - Paraffin-embedded human breast carcinoma tissue. |  Western Blot: LKB1 phosphospecific Antibody [NBP1-19951] - extracts from CV-1 forsklin cells. |
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Jump to: Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsLysates (2)Peptides and ProteinsPrimary Antibodies (17)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| LKB1 Antibody | NBP1-87817 | Hu | IF, IHC-P, WB | (3) | | | | | LKB1 Antibody | NBP1-54989 | Bv, Ca, Ch, Hu, Mu, Rt, Ze | IHC-P, WB | (2) | | | | | LKB1 Antibody | NBP1-61458 | Hu, Mu | ELISA, IF, IHC | (2) | | | | | LKB1 Antibody (4H12) | NBP1-51683 | Hu, Mk, Mu | ELISA, IF, WB | (2) | | | | | LKB1 Antibody | NBP1-03045 | Hu, Mu | IHC-P, WB | (2) | | | | | ... and 12 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Rabbit IgG Antibody [HRP] | NB730-H | Rb | ELISA, ICC, IHC-P, WB | | (5) | | | | Rabbit IgG Antibody [FITC] | NB730-F | Rb | ICC, IHC-P | | (1) | | | | Rabbit IgG Antibody [Biotin] | NB730-B | Rb | ELISA, ICC, IHC-P, WB | | | | | | Rabbit IgG, H/L Chains Antibody [DyLight 488] | NBP1-72944 | Rb | FLISA, IF, WB | (3) | | | | | Rabbit IgG Antibody [Alkaline Phosphatase] | NB730-AP | Rb | ELISA, ICC, IHC-P, WB | | (1) | | | | See All » |
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