LDL Receptor Antibody (NBP1-06709B)
LDL Receptor Antibody [Biotin]
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anti-LDLCQ2 antibody, anti-LDL R antibody, anti-Low-density lipoprotein receptor antibody, anti-FH antibody, anti-Cu2+ oxidised low density lipoprotein antibody, anti-apolipoprotein antibody, anti-low density protein antibody, anti-Low density lipoprotein receptor familial hypercholesterolemia antibody, anti-Low Density Lipoprotein Receptor antibody, anti-LDLR antibody, anti-FHC antibody, |
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LDL Receptor Antibody [Biotin] Summary: | | Gene: | LDLR |
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| Purity: | Peptide affinity purified |
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| Host: | Rabbit |
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| | Specificity: | This is specific for both the unglycosylated and glycosylated forms of the LDL Receptor. |
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| Publications: | Antibody has at least 3 Background References. |
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| | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional LDL Receptor Products LDL Receptor Antibody [Biotin] Details: | Conjugate: | Biotin |
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| Immunogen: | Synthetic peptide made to an internal portion of the human protein (within residues 500-550). [Swiss-Prot# P01130] |
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| Localization: | Membrane; Single-pass type I membrane protein. Membrane ? clathrin-coated pit; Single-pass type I membrane protein. |
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Human. Immunogen has 100% homology with monkey and 92% homology with mouse. |
| Uses: | This antibody is useful for Western blot, where bands are seen ~95 kDa and ~160 kDa representing the unglycosylated and glycosylated forms of the LDL receptor, respectively. |
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| Dilutions: | Western Blot 0.5 ug/ml |
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| Unit Size: | 0.1 ml |
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| Concentration: | 1.41 mg/ml |
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| Positive Controls: | 1 Positive Controls |
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| Conjugated Antibodies: | 4 Conjugated Antibodies |
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Packaging: | Storage: | Store at 4 °C. Do not freeze. |
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| Buffer: | PBS |
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| Preservative: | No Preservative |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: The low density lipoprotein (LDL) receptor system coordinates the metabolism of cholesterol, an essential component of the plasma membrane of all mammalian cells. Study of this system has led to an enhanced understanding of the cellular basis of cholesterol homeostasis. It has also brought into focus an important mechanism of metabolic regulation--the process of receptor-mediated endocytosis (1). Data suggest that the juxtamembranous region of the cytoplasmic domain participates in protein:protein interactions that allow the low density lipoprotein receptor to cluster in coated pits (2). It has been shown that the family of LDL receptors may serve as viral receptors. Endocytosis of the Flaviviridae viruses, hepatitis C virus, GB virus C/hepatitis G virus, and bovine viral diarrheal virus (BVDV) was shown to be mediated by LDL receptors on cultured cells (3).
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Reviews (0) Related Products (31) Exploring LDL Receptor Working with LDL Receptor
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Working with LDL Receptor
LDL Receptor Antibody [Biotin] Images (0)
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Publications (3)LDL Receptor Antibody [Biotin] Background References:- Agnello V, et al. Proc Natl Acad Sci 96(22):12766-71, 1999
- Davis CG, et al. J Biol Chem 262(9):4075-82, 1987.
more... - Brown MS, et al. Proc Natl Acad Sci 76(7):3330-7, 1979.
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Jump to: Conjugated Antibodies, Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies
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Related ProductsConjugated AntibodiesPositive Controls| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Other Positive Controls |
Lysates (2)Peptides and ProteinsPrimary Antibodies (21)| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| LDL Receptor Antibody (C7) | NBP1-78159 | Bv, Hu | ICC, IF, IHC-P, IP, WB | (2) | (6) | | | | LDL Receptor Antibody | NBP1-06709 | Hu, Mk, Mu | WB | (1) | (3) | | | | LDL Receptor Antibody (EP1553Y) | NB110-57162 | Hu, Mu, Rt | FACS, ICC, IHC-P, IP, WB | (3) | (3) | | | | LDL Receptor Antibody | NBP1-87476 | Hu | IF, IHC-P, WB | (2) | | | | | LDL Receptor Antibody | NBP1-87579 | Hu | IF, IHC-P, WB | (1) | | | | | ... and 16 more. See All » |
RNAi (1)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Rabbit IgG Antibody [HRP] | NB730-H | Rb | ELISA, ICC, IHC-P, WB | | (5) | | | | Rabbit IgG Antibody [FITC] | NB730-F | Rb | ICC, IHC-P | | (1) | | | | Rabbit IgG Antibody [Biotin] | NB730-B | Rb | ELISA, ICC, IHC-P, WB | | | | | | Rabbit IgG, H/L Chains Antibody [DyLight 488] | NBP1-72944 | Rb | FLISA, IF, WB | (3) | | | | | Rabbit IgG Antibody [Alkaline Phosphatase] | NB730-AP | Rb | ELISA, ICC, IHC-P, WB | | (1) | | | | See All » |
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