LDL Receptor Antibody (H00003949-B01)

LDL Receptor Antibody

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LDL Receptor Antibody Summary:
Species:Hu
Applications:ELISA, WB
Clonality:Polyclonal
Gene:LDLR
Purity:Whole antisera
Host:Mouse
Specificity:LDLR - low density lipoprotein receptor (familial hypercholesterolemia),
 
Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
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LDL Receptor Antibody Details:
Immunogen:LDLR (AAH14514, 1 a.a. ~ 860 a.a) full-length human protein.
Species Reactivity:

Human. Other species not tested.

Applications:
Uses:Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot. GST tag alone is used as a negative control.
Dilutions:Western Blot 1:500, ELISA
Unit Size:0.05 ml
Concentration:This product is unpurified. Concentration is not relevant.
Positive Controls:1 Positive Controls
Notes:
This product is produced by and distributed for Abnova, a company based in Taiwan.
Packaging:
Storage:Aliquot and store at -20 °C or -80 °C. Avoid freeze-thaw cycles.
Buffer:This antibody is in antisera and the concentration is unavailable.
Preservative:No Preservative
Limitations:This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Gene Symbol: LDLR
Entrez3949 (Human)
Swiss ProtAAH14514 (Human)
 
Background:

The low density lipoprotein receptor (LDLR) gene family consists of cell surface proteins involved in receptor-mediated endocytosis of specific ligands. Low density lipoprotein (LDL) is normally bound at the cell membrane and taken into the cell ending up in lysosomes where the protein is degraded and the cholesterol is made available for repression of microsomal enzyme 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, the rate-limiting step in cholesterol synthesis. At the same time, a reciprocal stimulation of cholesterol ester synthesis takes place. Mutations in this gene cause the autosomal dominant disorder, familial hypercholesterolemia.

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Working with LDL Receptor

LDL Receptor Antibody Images (1)
Western Blot analysis of LDLR expression in transfected 293T cell line by LDLR MaxPab polyclonal antibody (B01).

Lane 1: LDLR transfected lysate(94.60 KDa).
Lane 2: Non-transfected lysate.
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Jump to: Positive Controls, Lysates, Peptides and Proteins, Primary Antibodies, RNAi, Secondary Antibodies

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LDL Receptor in Context


Research Areas related to LDL Receptor (2):
Novus Explorer for LDL Receptor gene

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