LC3C Antibody (NB110-74789)
LC3C Antibody
|
This product is fully covered under the Novus guarantee+ Policy.
Click
here for details.
|
|
Distributor Data...
|
|
anti-Microtubule-associated proteins 1A/1B light chain 3C antibody, anti-MAP1LC3C antibody, anti-MAP1A/MAP1B LC3 C antibody, anti-MAP1A/1B light chain 3 C antibody, anti-MAP1 light chain 3-like protein 3 antibody, anti-Autophagy-related ubiquitin-like modifier LC3C antibody, anti-Autophagy-related protein LC3 C antibody, |
|
|
LC3C Antibody Summary: | | Gene: | MAP1LC3C |
|---|
| Purity: | IgG purified |
|---|
| Host: | Sheep |
|---|
| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional LC3C Products LC3C Antibody Details: | Isotype: | IgG |
|---|
| Immunogen: | A synthetic peptide as a part of human microtubule-associated protein 1 light chain 3 gamma (MAP1LC3C, MAP1A/MAP1B LC3 C) conjugated to immunogenic carrier protein has been used as the immunogen. |
|---|
| Uses: | Immunohistochemistry-Paraffin/Frozen and Western Blot |
|---|
| Dilutions: | Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot 1-10 ug/ml |
|---|
| Unit Size: | 0.5 mg |
|---|
| Concentration: | lyoph |
|---|
|
Notes: Reconstitute in 0.5 ml of sterile water. Centrifuge to remove any insoluble material. When reconstituting, glycerol (1:1) may be added for an additional stability. Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
|---|
| Buffer: | Lyophilized in PBS |
|---|
| Preservative: | No Preservative |
|---|
| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
|---|
Background: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. FUNCTION: Probably involved in formation of autophagosomal vacuoles (autophagosomes). SUBUNIT: 3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. SUBCELLULAR LOCATION: Cytoplasm. Intracytoplasmic membrane; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note: LC3-II binds to the autophagic membranes. TISSUE SPECIFICITY: Most abundant in placenta, lung and ovary. The precursor molecule is cleaved by APG4B/ATG4B to form the cytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 and conjugated to phospholipid to form the membrane-bound form, LC3-II.
|
Reviews (0) Related Products (7) Exploring LC3C Working with LC3C
|
Jump to: Publications, Ask a Question
|
Working with LC3C
LC3C Antibody Images (0)
|
|
|
Publications (3)LC3C Antibody Background References:- He H, et al. J. Biol. Chem. 278 (31), 29278-29287(2003).
- Tanida I, et al. J. Biol. Chem. 279 (35), 36268-36276(2004).
more... - Gregory S.G, et al. Nature 441 (7091), 315-321(2006).
|
|
|
|
Ask a Scientist
Can't find an answer to your question about LC3C? Ask us by using live
chat or by submitting your questions below:
|
Jump to: Lysates, Peptides and Proteins, Primary Antibodies, Secondary Antibodies
|
Related ProductsLysates (1)Peptides and ProteinsPrimary Antibodies (5)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
|---|
| Sheep IgG Antibody [Texas Red] | NB7582 | Sh | FACS, FLISA, IF, IHC-Fr, IHC-P | | (1) | | | | Sheep IgG Antibody [Alkaline Phosphatase] | NB120-7112 | Sh | ELISA, IHC-Fr, IHC-P, WB | | (2) | | | | Sheep IgG Antibody [Rhodamine] | NB120-6744 | Sh | FACS, IF, IHC-Fr, IHC-P | | (1) | | | | Sheep IgG, H/L chains Antibody [DyLight 488] | NBP1-72996 | Sh | FLISA, IF, WB | (1) | | | | | Sheep IgG, H/L chains Antibody [DyLight 549] | NBP1-72997 | Sh | FLISA, IF, WB | (1) | | | | | See All » |
|
|
