LC3B Antibody (NB110-74841)
LC3B Antibody
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anti-Autophagy related protein LC3 A antibody, anti-Microtubule associated proteins 1A/1B light chain 3 antibody, anti-Microtubule associated protein 1 light chain 3 alpha antibody, anti-MAP1BLC3 antibody, anti-MAP1ALC3 antibody, anti-MAP1A/MAP1B LC3 A antibody, anti-MAP1A/1B light chain 3 A antibody, anti-MAP1 light chain 3 like protein 1 antibody, anti-LC3A antibody, anti-Autophagy related ubiquitin like modifier LC3 A antibody |
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LC3B Antibody Summary: | | Gene: | MAP1LC3B |
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| Purity: | Whole antisera |
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| Host: | Rabbit |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional LC3B Products LC3B Antibody Details: | Immunogen: | A synthetic peptide as a part of rat and moue microtubule-associated proteins 1A/1B light chain 3B (MAP1A/MAP1B LC3 B, Map1lc3b) conjugated to an immunogenic carrier protein has been used as the immunogen. |
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| Marker: | Autophagosomes Marker |
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| Uses: | Immunohistochemistry-Paraffin/Frozen and Western Blot |
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| Dilutions: | Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot 1:300 to 1:2000 |
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| Unit Size: | 0.15 ml |
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| Concentration: | lyoph |
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Notes: Reconstitute in 0.15 ml of sterile water. Centrifuge to remove any insoluble material. When reconstituting, glycerol (1:1) may be added for an additional stability. Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | Lyophilized |
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| Preservative: | No Preservative |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. FUNCTION: Probably involved in formation of autophagosomal vacuoles (autophagosomes). May mediate MAPlA and MAPlB microtubule binding activity during development of the nervous system SUBUNIT: 3 different light chains, LC1, LC2 and LC3, can associate with MAP1A and MAP1B proteins. SUBCELLULAR LOCATION: Cytoplasm. Intracytoplasmic membrane; Lipid-anchor. Cytoplasmic vesicle, autophagosome membrane; Lipid-anchor. Note: LC3-II binds to the autophagic membranes.
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Reviews (0) Related Products (18) Exploring LC3B Working with LC3B
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Working with LC3B
LC3B Antibody Images (0)
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Publications (1)LC3B Antibody Background References:- OSM00026W,OSM00027W
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