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L1CAM Antibody (UJ127)

 (2 Publications)
 (1 Review)
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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NB600-555
    • Availability
      Product Discontinued

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L1CAM Antibody (UJ127) Summary

Immunogen
Homogenous suspension of 16 week human fetal brain
Localization
Cell membrane.
Marker
Axon Marker
Specificity
NB600-555 is useful in the identification of primitive neuroectodermal tumors. It binds to tumors of neuroectodermal and glial origin. It does not bind to pediatric or adult brain.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
L1CAM
Purity
Protein G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:1000
  • Immunohistochemistry-Paraffin 1:100
  • Immunoprecipitation 2 ug/mg
  • Western Blot 1 - 2 ug/ml
Application Notes
WB: Detects an approx. 220 - 240 kDa, which corresponds to the predicted molecular weight of L1CAM.
Reviewed Applications
Read 1 Review rated 4
using
NB600-555 in the following applications:
Publications
Read Publications using
NB600-555 in the following applications:

  • WB
    1 publication

Reactivity Notes

Hamster reactivity reported in scientific literature (PMID: 20335502).

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4) and 0.2% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Protein G purified

Alternate Names for L1CAM Antibody (UJ127)

  • antigen identified by monoclonal R1
  • CAML1
  • CAML1N-CAML1
  • CD171 antigen
  • CD171
  • HSAS
  • HSAS1
  • L1 cell adhesion molecule
  • L1CAM
  • MASA
  • MIC5
  • N-CAM-L1
  • NCAM-L1
  • neural cell adhesion molecule L1
  • S10
  • SPG1

Background

The L1CAM gene, which is located in Xq28, is involved in three distinct conditions: 1) HSAS (hydrocephalus-stenosis of the aqueduct of Sylvius); 2) MASA (mental retardation, aphasia, shuffling gait, adductus thumbs); and 3) SPG1 (spastic paraplegia). The L1, neural cell adhesion molecule (L1CAM) also plays an important role in axon growth, fasciculation, neural migration and in mediating neuronal differentiation. Expression of L1 protein is restricted to tissues arising from neuroectoderm.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for L1CAM Antibody (NB600-555)(2)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 1 application: WB.


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WB
(1)
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(1)
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Review for L1CAM Antibody (NB600-555) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using NB600-555:
Filter by Applications
WB
(1)
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Human
(1)
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Images Ratings Applications Species Date Details
  4
reviewed by:
Huafeng Zhang
 WB Human 08/04/2010
View

Summary

ApplicationWestern Blot
Sample TestedMDA-231 cell lysate, Sample Amount: 100ug
SpeciesHuman

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FAQs for L1CAM Antibody (NB600-555). (Showing 1 - 1 of 1 FAQs).

  1. Hello. For the following product, could you let us know the concentration of sodium azide? #NB600-555 L1CAM Antibody (UJ127) Buffer: 10mM PBS [pH7.4] with 0.2% BSA Preservative: Sodium Azide
    • The L1CAM antibody with catalogue number NB600-555 is supplied in 10mM PBS pH 7.4, with 0.2% BSA and 0.09% sodium azide.

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Blogs on L1CAM.

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Identifying tumoral and stromal transcriptomes that underlie tumor plasticity and stromal neuroinflammatory response in brain metastasis
By Jamshed Arslan, Pharm. D., PhD. Cancers in the brain often come from tumors elsewhere in the body. Several adaptive mechanisms influence brain metastasis, such as blood brain barrier leakage that can be induced by ...  Read full blog post.

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Recent Reviews

4
5
0
4
1
3
0
2
0
1
0
 
 Huafeng Zhang
08/04/2010
Application: WB
Species: Human
read this review

Bioinformatics

Gene Symbol L1CAM
Entrez
Uniprot