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Kallikrein 6/Neurosin Partial Protein

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-74344
    • Availability
      Product Discontinued

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Kallikrein 6/Neurosin Partial Protein Summary

Description
A partial protein with a GST tag of KLK6.Source: bacteria
Protein/Peptide Type
Partial Protein
Gene
KLK6

Applications/Dilutions

Dilutions
  • Western Blot
Application Notes
This product was tested on western blot.

Packaging, Storage & Formulations

Storage
Store at -80C. Avoid freeze-thaw cycles.
Buffer
0.1M Tris-HCl (pH 6.8) buffer containing 0.2M DTT, 4% SDS, 0.2% Bromophenol blue and 20% Sucrose.
Concentration
LYOPH
Reconstitution Instructions
Centrifuge prior to opening. Reconstitute with sterilized PBS to a final concentration of 1mg/ml. Vortex followed by Centrifuge again to pellet the solution.

Notes

Add 200ul of distilled water. Final concentration is 1 mg/ml.

Alternate Names for Kallikrein 6/Neurosin Partial Protein

  • Bssp
  • EC 3.4.21
  • EC 3.4.21.-
  • hK6
  • kallikrein 6 (neurosin, zyme)
  • Kallikrein 6
  • kallikrein-6
  • kallikrein-related peptidase 6
  • KLK6
  • Klk7
  • Neurosin
  • Protease M
  • protease, serine, 18
  • PRSS18
  • PRSS9
  • PRSS9MGC9355
  • Serine protease 18
  • Serine protease 9
  • SP59
  • Zyme

Background

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Kallikrein 6, or KLK6, shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. It degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. KLK6 may be involved in regulation of axon outgrowth following spinal cord injury. KLK6 has also been shown to promote cell proliferation, migration, and invasion. It is upregulated in several types of cancers including colon and ovarian cancers.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol KLK6