Kallikrein 6/Neurosin Partial Protein Summary
| Description |
A partial protein with a GST tag of KLK6.Source: bacteria |
| Protein/Peptide Type |
Partial Protein |
| Gene |
KLK6 |
Applications/Dilutions
| Dilutions |
|
| Application Notes |
This product was tested on western blot. |
Packaging, Storage & Formulations
| Storage |
Store at -80C. Avoid freeze-thaw cycles. |
| Buffer |
0.1M Tris-HCl (pH 6.8) buffer containing 0.2M DTT, 4% SDS, 0.2% Bromophenol blue and 20% Sucrose. |
| Concentration |
LYOPH |
| Reconstitution Instructions |
Centrifuge prior to opening. Reconstitute with sterilized PBS to a final concentration of 1mg/ml. Vortex followed by Centrifuge again to pellet the solution. |
Notes
Add 200ul of distilled water. Final concentration is 1 mg/ml.
Alternate Names for Kallikrein 6/Neurosin Partial Protein
Background
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Kallikrein 6, or KLK6, shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. It degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. KLK6 may be involved in regulation of axon outgrowth following spinal cord injury. KLK6 has also been shown to promote cell proliferation, migration, and invasion. It is upregulated in several types of cancers including colon and ovarian cancers.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are
guaranteed for 1 year from date of receipt.
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