Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 233 of KLK6
Localization:
Nucleus, Nucleolus
Species Reactivity:
Tested in human. Not yet tested in any other species.
Applications:
Uses:
Western blot
Dilutions:
Western Blot
Unit Size:
0.1 ml
Concentration:
0.88 mg/ml
Packaging:
Storage:
Store at -20 °C. Avoid freeze-thaw cycles.
Buffer:
0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7.0).
Preservative:
0.01% Thimerosal
Limitations:
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimer's disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene.