Kallikrein 6 Antibody (NBP1-06497)
Kallikrein 6 Antibody
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anti-TK antibody, anti-SP 59 antibody, anti-PRSS 9 antibody, anti-PRSS 18 antibody, anti-Protease serine 9 antibody, anti-Protease serine 18 antibody, anti-mGK1 antibody, anti-mGK 1 antibody, anti-KLK9 antibody, anti-KLK 9 antibody, anti-Klk 7 antibody, anti-KLK 6 antibody, anti-Kallikrein6 antibody, anti-Kallikrein related peptidase 6 antibody, anti-Kallikrein 6 precursor antibody, anti-hK 6 antibody, anti-Protease M antibody, anti-Bssp antibody, Anti-ZYME antibody, anti-Tissue kallikrein antibody, anti-SP59 antibody, anti-Serine protease 9 antibody, anti-Serine protease 18 antibody, anti-PRSS9 antibody, anti-PRSS18 antibody, anti-Neurosin
Zyme antibody, anti-NEUROSIN antibody, anti-MGC9355 antibody, anti-Klk7 antibody, anti-Klk6 antibody, anti-Kallikrein-6 antibody anti-PRSS18 antibody, anti-hK6 antibody, |
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Kallikrein 6 Antibody Summary: | | Gene: | KLK6 |
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| Purity: | Whole antisera |
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| Host: | Rabbit |
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| | | Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur. |
View Additional Kallikrein 6 Products Kallikrein 6 Antibody Details: | Immunogen: | Full length human KLK6 protein [Swiss-Prot# Q92876] expressed in E. coli. |
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| Localization: | Secreted. Nucleus ? nucleolus. Cytoplasm. Mitochondrion. Microsome. Note= In brain, detected in the nucleus of glial cells and in the nucleus and cytoplasm of neurons. Detected in the mitochondrial and microsomal fractions of HEK-293 cells and released in |
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Human. Sequence has 85% identity with canine, 82% identity with horse and 80% identity with bovine. |
| Uses: | This antibody is useful for Western blot, where a band is seen ~38kDa due to glycosylation. |
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| Dilutions: | Western Blot 1:1000,
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| Unit Size: | 0.1 ml (also available: 0.025 ml (sample size)) |
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| Concentration: | This product is unpurified. Concentration is not relevant. |
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| Positive Controls: | 1 Positive Controls |
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Packaging: | Storage: | Store at 4 °C short term. Aliquot and store at -20 °C long term. Avoid freeze-thaw cycles. |
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| Buffer: | Whole sera |
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| Preservative: | 0.1% Sodium Azide |
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| Limitations: | This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months. |
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Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Kallikrein 6, or KLK6, shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. It degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. KLK6 may be involved in regulation of axon outgrowth following spinal cord injury. KLK6 has also been shown to promote cell proliferation, migration, and invasion and is upregulated in several types of cancers including colon and ovarian cancers.
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Images (1) Reviews (0) Related Products (19) Exploring Kallikrein 6 Working with Kallikrein 6
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Jump to: Publications, Images, Ask a Question
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Working with Kallikrein 6
Kallikrein 6 Antibody Images (1) Western Blot: KLK6 Antibody [NBP1-06497] - Human salivary lysates. |
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Publications (4)Kallikrein 6 Antibody Background References:- Blaber SI et al. The autolytic regulation of human kallikrein-related peptidase 6. Biochemistry. 46(17):5209-17 (2008).
- Klucky B et al. Kallikrein 6 induces E-cadherin shedding promotes cell proliferation, migration, invasion. Cancer Res. 67(17):8198-206 (2008)
more... - Henkhaus RS et al. Caveolin-1-mediated expression secretion of kallikrein 6 in colon cancer cells. Neoplasia 10(2):140-8 (2008)
- Kuzmanov U, et al. Differential n-glycosylation of kallikrein 6 derived from ovarian cancer cells or the central nervous system. Mol Cell Proteomics. [Epub ahead of print] (Dec. 2008)
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Related ProductsPositive ControlsLysates (2)Peptides and ProteinsPrimary Antibodies (10)RNAi (3)Secondary Antibodies| Name | Catalog# | Reactivity | Applications | Images | Publications | Reviews | |
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| Rabbit IgG Antibody [HRP] | NB730-H | Rb | ELISA, ICC, IHC-P, WB | | (5) | | | | Rabbit IgG Antibody [FITC] | NB730-F | Rb | ICC, IHC-P | | (1) | | | | Rabbit IgG Antibody [Biotin] | NB730-B | Rb | ELISA, ICC, IHC-P, WB | | | | | | Rabbit IgG, H/L Chains Antibody [DyLight 488] | NBP1-72944 | Rb | FLISA, IF, WB | (3) | | | | | Rabbit IgG Antibody [Alkaline Phosphatase] | NB730-AP | Rb | ELISA, ICC, IHC-P, WB | | (1) | | | | See All » |
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Novus Explorer for Kallikrein 6 gene
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