Note: Not all species have been tested for usefulness with this product. Only those species listed have been tested. We cannot make any guarantees about additional reactivities which may or may not occur.
The epitope recognized by this antibody maps to a region between residue 1100 and 1150 of human insulin receptor substrate 2 using the numbering given in entry NP_003740.2 (GeneID 8660).
Species Reactivity:
Human.
Applications:
Uses:
This antibody is useful for Western blot and Immunoprecipitation
Dilutions:
Western Blot 1:2000-1:10000
immunoprecipitation 2-5 ug/mg lysate
Unit Size:
0.1 ml
Concentration:
0.2 mg/ml
Packaging:
Storage:
Store at 4 °C. Do not freeze.
Buffer:
Tris-buffered Saline containing 0.1% BSA
Preservative:
0.09% Sodium Azide
Limitations:
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.
This gene encodes the insulin receptor substrate 2, a cytoplasmic signaling molecule that mediates effects of insulin, insulin-like growth factor 1, and other cytokines by acting as a molecular adaptor between diverse receptor tyrosine kinases and downstream effectors. The product of this gene is phosphorylated by the insulin receptor tyrosine kinase upon receptor stimulation, as well as by an interleukin 4 receptor-associated kinase in response to IL4 treatment.
Western Blot and Immunoprecipitation: IRS2 Antibody [NB100-68243] - Detection of Human IRS2 NB100-68243. IRS2 was also immunoprecipitated by rabbit anti-IRS2 antibodies NB100-68242 and NB100-68244.