IQGAP1 Antibody

Species: Hu Applications: IHC Clonality: Polyclonal	Gene: IQGAP1 Purity: Immunogen affinity purified Host: Rabbit
Specificity: IQGAP1
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*Note not all species have been tested for reactivity. Only those species listed have been tested. We cannot make any guarantees about additional reactivities or cross reactivities beyond those that have been tested. This antibody may or may not react with other species.

Isotype:	IgG
Immunogen:	The epitope recognized by this antibody maps to a region between residue 1 and 50 of human motif containing GTPase activating protein 1 using the numbering given in entry NP_003861.1 (GeneID 8826).

Entrez:	8826 (Human)
Swiss Prot:	NP_003861.1 (Human)
Related Genes:	AGT, 2010317E24RIK, ANG, CDC42, RAC1, CTNNB1, RACGAP1, AGTRAP, AGTR1A, CALM3, CALM2, CALM1, AGTR1, AGTR1B, CDH1, REN, SLC33A1, ATM, SERPINB9D, AGTR2, HRAS1, AKT1, KRAS, MAPK1, RHO, RHOD, EA2, CLIP1, HGF, AVP, MAPK3, IQGAP2, SEC13, GSTA4, POMC, APC, ARF1, NR1I2, KNG1, EGF

IQGAP1 (IQ motif containing GTPase activating protein 1) interacts with the Rho-family GTPases, CDC42 and RAC1. It has been shown to localize to sites of cell-cell contact and regulate cadherin-mediated cell-cell adhesion. In addition to its role in cell adhesion, it is also involved in cell polarization and migration.

Reactivity:	Human

Uses:	This antibody is useful for immunohistochemistry.
Dilutions:	Immunohistochemistry: 1:100 - 1:500,

Buffer:	Tris-buffered Saline containing 0.1% BSA
Storage:	Store at 4C. Do not freeze.
Preservative:	0.09% Sodium Azide
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.