IQGAP1 Antibody (1260) (NB100-63052)

IQGAP1 Antibody (1260) (NB100-63052) (0.1 mg)

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	Catalog Number	NB100-63052
	Size(s)	0.1 mg	Price: N/A
	Availability	Discontinued
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	View All IQGAP1 Primary Antibodies

anti-SAR1 antibody, anti-p195RasGAP-like with IQ motifs antibody, anti-KIAA0051ras GTPase-activating-like protein IQGAP1 antibody, anti-HUMORFA01 antibody, anti-IQ motif containing GTPase activating protein 1 antibody

IQGAP1 Antibody (1260) Summary:

Species:	Mu	Gene:	IQGAP1
Applications:	WB, ELISA, IHC-Fr	Purity:	Affinity purified
Clonality:	Monoclonal	Host:	Human
Specificity:	NB100-63052 binds to the C-terminal 122 amino acids of mKIAA0051, also known as Murine IQ motif containing GTPase activating protein 1.The mKIAA0051 protein (IQGAP1) has a fundamental role in cell motility and invasion. It binds to activated CDC42 but does not stimulate its GTPase activity. It also associates with calmodulin and regulates cadherin-based cell adhesion. Potentially mKIAA0051 serves as an assembly scaffold for the organization of a multimolecular complex that would interface incoming signals to the reorganization of the actin cytoskeleton at the plasma membrane. HCA008 may bind to the human Ras GTPase-activating-like protein IQGAP1 (p195), due to 98% sequence identity in the antigen region.
Publications:	NB100-63052 has at least 2 Background References

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Lysates	Peptides and Proteins
Primary Antibodies	RNAi
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IQGAP1 Antibody (1260) Details:

Clone:	1260
Immunogen:	Fusion protein of a domain of murine mKIAA0051 (amino acid residues 1536-1675, MW 14 kDa) expressed in E. coli.

Species Reactivity:

Mouse. Not yet tested in other species.

Applications:

Uses:	This antibody is useful for ELISA, Immunohistochemistry-Frozen, Western Blot
Dilutions:	ELISA Immunohistochemistry-Frozen Western Blot
Unit Size:	0.1 mg
Concentration:	Please see the vial label for concentration.

Packaging:

Storage:	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Preservative:	Sodium Azide
Limitations:	This product is for research use only and is not approved for use in humans or in clinical diagnosis. Products are guaranteed for 6 months from date of receipt, except for peptides and proteins which are guaranteed for 3 months.

Gene Symbol: IQGAP1

Related Genes:

Images (2)


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IQGAP1 Antibody (1260) Images (2)

	Western Blot: KIAA0051 Antibody (1260) [NB100-63052] - analysis of various adult mouse tissues showing a band at approx. 191kDa when probed with 0.5ug/ml NB100-63052 followed by Goat anti Human IgG F(ab')2: HRP

	Immunohistochemistry-Frozen: KIAA0051 Antibody (1260) [NB100-63052] - Staining of frozen sections from 10 week-old ICR mice stained with 2ug/ml KIAA0051

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Publications (2)

IQGAP1 Antibody (1260) Background References:

Ohara, R. et al. (2006) Antibodies for proteomic research: comparison of traditional immunization with recombinant antibody technology. Proteomics. 6: 2638-2646.
Mataraza, J. M. et al. (2003) IQGAP1 promotes cell motility invasion. J. Biol. Chem. 278: 41237-41245.